边缘智力功能与精神病：成人精神健康状况调查证据。

Borderline intellectual functioning and psychosis: Adult Psychiatric Morbidity Survey evidence.

机构信息

A. Hassiotis, PhD, M. Noor, MSc, P. Bebbington, PhD, A. Afia, PhD, UCL Division of Psychiatry, London, UK; J. Wieland, PhD, Poli-plus, Leiden, The Netherlands; T. Qassem, MD, Division of Mental Health and Well-being, University of Warwick, Coventry, UK

出版信息

Br J Psychiatry. 2017 Jul;211(1):50-51. doi: 10.1192/bjp.bp.116.190652. Epub 2017 Apr 6.

DOI:10.1192/bjp.bp.116.190652

PMID:28385706

Abstract

Borderline intellectual functioning (BIF) is associated with several neuropsychological deficits. We used national data to establish the prevalence of psychosis and psychotic symptoms, and the role of potential mediators. The BIF group were more than twice as likely to have probable psychosis (adjusted odds ratio (OR)=2.3, 95% CI 1.4-4.0) and to report hallucinations (adjusted OR = 2.9, 95% CI 1.9-4.4) but not persecutory ideation. Salient mediators were depressive symptoms and the cumulative total of life events. Our findings suggest mechanisms other than drug use that are contributing to the strong relationship between BIF and severe mental illness and that may be amenable to treatment.

摘要

边缘智力功能 (BIF) 与多种神经心理缺陷有关。我们使用国家数据来确定精神病和精神病症状的患病率，以及潜在中介因素的作用。BIF 组发生可能的精神病的可能性是两倍多（调整后的优势比 (OR)=2.3，95%CI 1.4-4.0），并且报告幻觉（调整后的 OR=2.9，95%CI 1.9-4.4）的可能性更高，但妄想症的报告则没有。明显的中介因素是抑郁症状和生活事件的累积总数。我们的研究结果表明，导致 BIF 与严重精神疾病之间存在强关联的原因除了药物使用之外，还有其他机制，这些机制可能是可以治疗的。