婴儿期短暂性高磷酸酶血症的动态变化

Dynamic aspects in transient hyperphosphatasaemia of infancy.

作者信息

Rasmussen K T, Carstensen H

机构信息

Department of Paediatrics, Rigshospitalet, University Hospital, Copenhagen, Denmark.

出版信息

Acta Paediatr Scand. 1988 May;77(3):457-9. doi: 10.1111/j.1651-2227.1988.tb10680.x.

DOI:10.1111/j.1651-2227.1988.tb10680.x

PMID:2839002

Abstract

A 20-month-old boy with absence epilepsy was found to have a strikingly elevated serum alkaline phosphatase (AP) at start of treatment with valproic acid. The monitoring of this therapy made it possible to follow the elimination of AP which was shown to be a first order kinetic with a half-life of 6.1 days. A concurrent adenovirus infection was diagnosed.

摘要

一名20个月大的失神癫痫男孩在开始使用丙戊酸治疗时，血清碱性磷酸酶（AP）显著升高。对该治疗的监测使得追踪AP的消除情况成为可能，结果显示其消除呈一级动力学，半衰期为6.1天。同时诊断出腺病毒感染。