存在青光眼的眼中，Descemet膜内皮角膜移植术（DMEK）早期移植失败
Descemet membrane endothelial keratoplasty (DMEK) early stage graft failure in eyes with preexisting glaucoma.
作者信息
Treder Maximilian, Alnawaiseh Maged, Eter Nicole
机构信息
Department of Ophthalmology, University of Muenster Medical Center, Domagkstraße 15, 48149, Muenster, Germany.
出版信息
Graefes Arch Clin Exp Ophthalmol. 2017 Jul;255(7):1417-1421. doi: 10.1007/s00417-017-3668-z. Epub 2017 Apr 8.
PURPOSE
To evaluate the effect of a preexisting glaucoma on the early postoperative outcome of a descemet membrane endothelial keratoplasty (DMEK).
METHODS
All patients who underwent DMEK surgery at the Department of Ophthalmology of the University of Muenster with a follow-up of at least 3 months (90d) were included in this study. The best corrected distance visual acuity (BCDVA), the intraocular pressure (IOD), the rate of re-keratoplasty and the rebubbling rate were inter alia recorded. The results of patients with (group 1) and without a preexisting glaucoma (group 2) were compared.
RESULTS
74 eyes of 59 patients with a mean follow-up of 152 ± 70 days were included. 65 eyes were in group 1 and 9 eyes in group 2. The BCDVA significantly improved in both groups after surgery (p < 0.03). The Re-keratoplasty rate (p = 0.172), the number of rebubblings per patient (p = 0.571) and the rebubbling rate (p = 0.939) were not significantly different in patients without glaucoma compared to patients with a preexisting glaucoma.
CONCLUSIONS
In the early stage outcome of DMEK no significant impact of a preexisting glaucoma was found.
目的
评估既往青光眼对Descemet膜内皮角膜移植术（DMEK）术后早期结果的影响。
方法
纳入在明斯特大学眼科接受DMEK手术且随访至少3个月（90天）的所有患者。特别记录最佳矫正远视力（BCDVA）、眼压（IOD）、再次角膜移植率和气泡注入率。比较有（第1组）和无既往青光眼（第2组）患者的结果。
结果
纳入59例患者的74只眼，平均随访152±70天。第1组65只眼，第2组9只眼。两组术后BCDVA均显著改善（p<0.03）。与有既往青光眼的患者相比，无青光眼患者的再次角膜移植率（p=0.172）、每位患者的气泡注入次数（p=0.571）和气泡注入率（p=0.939）无显著差异。
结论
在DMEK的早期结果中，未发现既往青光眼有显著影响。
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