Humphreys Susan, Rosen Derek, Housden Tessa, Taylor Julia, Schibler Andreas
Department of Anaesthesia, Lady Cilento Children's Hospital, South Brisbane, Qld, Australia.
Paediatric Critical Care Research Group, Mater Research University of Queensland, South Brisbane, Qld, Australia.
Paediatr Anaesth. 2017 Jun;27(6):616-620. doi: 10.1111/pan.13151. Epub 2017 Apr 10.
Transnasal Humidified Rapid-Insufflation Ventilatory Exchange has been shown to safely prolong the safe apnea time in well children post induction of anesthesia and is rapidly becoming a new standard for apneic oxygenation in adults. The same oxygenation technique is described as nasal high flow and can be used in infants and children at risk of apnea during anesthesia.
We investigated the use of nasal high flow oxygen delivery during anesthesia in children with abnormal airways requiring tubeless airway assessment or surgery.
Data and outcomes of pediatric patients receiving nasal high flow for upper airway procedures were analyzed. Four categories were defined: (i) tubeless airway surgery, (ii) flexible bronchoscopy, (iii) expected difficult airway, and (iv) comorbidity related risk of apnea. Anesthesia was induced intravenously or with sevoflurane (4-8%) and then converted to total intravenous anesthesia aiming for spontaneous ventilation. Age appropriate nasal high flow cannulae were secured with 100% oxygen delivery at weight-related flow rates. Topicalization of the airway was achieved with lignocaine. Complication rates of desaturation requiring interruption of procedure for rescue oxygenation were recorded.
Twenty children were analyzed with age range of 5 days to 11 years, ASA 1-4, and weight range 3-57 kg. Fifteen were induced with sevoflurane and 100% oxygen, five received total intravenous anesthesia only. All children received Optiflow™ nasal high flow and intravenous anesthesia during their procedure. Average SpO recorded was 96% with lowest SpO 77%. One required rescue oxygenation. Median length of procedure was 32 min, (range 3-61). Most common indication was tubeless airway surgery but seven children had more than one indication.
Nasal high flow can be used in spontaneously breathing children with abnormal airways for maintenance of oxygenation during anesthesia for tubeless airway procedures.
经鼻湿化快速充气通气交换已被证明能安全延长健康儿童麻醉诱导后的安全无呼吸时间,并迅速成为成人无呼吸氧合的新标准。同样的氧合技术被称为鼻高流量,可用于麻醉期间有呼吸暂停风险的婴幼儿。
我们研究了鼻高流量给氧在气道异常、需要进行无管气道评估或手术的儿童麻醉中的应用。
分析接受鼻高流量进行上气道手术的儿科患者的数据和结果。定义了四类:(i)无管气道手术,(ii)可弯曲支气管镜检查,(iii)预期困难气道,以及(iv)合并症相关的呼吸暂停风险。静脉注射或使用七氟醚(4-8%)诱导麻醉,然后转换为全静脉麻醉以维持自主通气。根据年龄选择合适的鼻高流量插管,以与体重相关的流速输送100%的氧气。使用利多卡因使气道表面麻醉。记录因血氧饱和度下降需要中断手术进行抢救性氧合的并发症发生率。
分析了20名儿童,年龄范围为5天至11岁,美国麻醉医师协会(ASA)分级为1-4级,体重范围为3-57千克。15名儿童用七氟醚和100%氧气诱导麻醉,5名仅接受全静脉麻醉。所有儿童在手术过程中均接受了Optiflow™鼻高流量给氧和静脉麻醉。记录的平均血氧饱和度为96%,最低血氧饱和度为77%。1名儿童需要进行抢救性氧合。手术的中位时长为32分钟(范围为3-61分钟)。最常见的适应证是无管气道手术,但7名儿童有不止一个适应证。
鼻高流量可用于气道异常的自主呼吸儿童,在无管气道手术麻醉期间维持氧合。