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[前列腺切除术总病例数超过1000例的外科医生进行耻骨后和机器人辅助根治性保留神经前列腺切除术后功能结果的比较]

[Comparison of functional outcomes after retropubic and robot-assisted radical nerve-sparing prostatectomy conducted by surgeons with total caseloads of over 1000 prostatectomies].

作者信息

Pushkar D Yu, Dyakov V V, Vasilyev A O, Kotenko D V

机构信息

Department of Urology, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia.

出版信息

Urologiia. 2017 Apr(1):50-53. doi: 10.18565/urol.2017.1.50-53.

Abstract

AIM

To compare the functional outcomes of bilateral nerve-sparing robot-assisted radical prostatectomy (RARP) and radical retropubic prostatectomy (RRP) at 12 months after surgery.

MATERIALS AND METHODS

This is a retrospective study of two groups, each of 50 sexually active patients with localized low risk prostate cancer. The first group comprised patients who underwent RRP, while the second underwent RARP. All operations were carried out sequentially from January to August 2015 using nerve-sparing technique. The study involved only two surgeons each having a total caseload of over 1000 prostatectomies of one of the two types. Patients of each group were operated on only by one of the two surgeons. Adjusted for negative treatment outcomes, the between-group comparison was conducted regarding the number of continent patients, temporal changes in urinary function, the number of patients with restored erectile function and temporal changes in its recovery.

RESULTS

At 12 months after surgery, complete continence was reported in 49 (98%) patients of the RARP group and in 48 (96%) patients of the RRP group. Among patients with restored continence, the time to attain complete continence was 4 months in the RARP group and 6 months in the RRP group (p<0.05). Sexual function recovery at 12 months follow-up after surgery was found satisfactory in 37 (74%) patients of the RARP group and in 12 (24%) of the RRP group. Recovery of erectile function after RARP was faster: in the RARP group erections at 3 months were reported in 32% of patients, while in the RRP group only in 4% (p<0.05).

CONCLUSIONS

The study findings showed the superiority of RARP over RRP performed by nerve-sparing technique in restoring continence and erectile function.

摘要

目的

比较双侧保留神经机器人辅助根治性前列腺切除术(RARP)和耻骨后根治性前列腺切除术(RRP)术后12个月的功能结局。

材料与方法

这是一项对两组进行的回顾性研究,每组有50例有性生活的局限性低危前列腺癌患者。第一组包括接受RRP的患者,第二组接受RARP。所有手术均在2015年1月至8月期间采用保留神经技术依次进行。该研究仅涉及两名外科医生,每位医生两种手术类型之一的总病例数均超过1000例。每组患者仅由两名外科医生中的一名进行手术。在调整了阴性治疗结局后,对两组间的控尿患者数量、尿功能的时间变化、勃起功能恢复的患者数量及其恢复的时间变化进行了比较。

结果

术后12个月时,RARP组49例(98%)患者和RRP组48例(96%)患者报告完全控尿。在控尿恢复的患者中,RARP组达到完全控尿的时间为4个月,RRP组为6个月(p<0.05)。术后12个月随访时,RARP组37例(74%)患者和RRP组12例(24%)患者的性功能恢复情况令人满意。RARP术后勃起功能恢复更快:RARP组3个月时有32%的患者报告有勃起,而RRP组仅为4%(p<0.05)。

结论

研究结果显示,在恢复控尿和勃起功能方面,保留神经技术的RARP优于RRP。

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