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经导管主动脉瓣植入术:老年及高危重度主动脉瓣狭窄患者治疗领域的一次变革。

Transcatheter aortic valve implantation: a revolution in the therapy of elderly and high-risk patients with severe aortic stenosis.

作者信息

Kilic Teoman, Yilmaz Irem

机构信息

Invasive Cardiology Research and Application Unit, Department of Cardiology, Kocaeli University, Kocaeli, Turkey.

Department of Cardiology, Kocaeli University, Kocaeli, Turkey.

出版信息

J Geriatr Cardiol. 2017 Mar;14(3):204-217. doi: 10.11909/j.issn.1671-5411.2017.03.002.

Abstract

Transcatheter aortic valve implantation (TAVI) represents a real revolution in the field of interventional cardiology for the treatment of elderly or high-risk surgical patients with severe symptomatic aortic valve stenosis. Today, TAVI seems to play a key and a reliable role in the treatment of intermediate and maybe low-risk patients with severe aortic stenosis. TAVI has also evolved from a complex and hazardous procedure into an effective and safe therapy by the development of new generation devices. This article aims to review the background and future of TAVI, clinical trials and registries with old and new generation TAVI devices and to focus on some open issues related to post-procedural outcomes.

摘要

经导管主动脉瓣植入术(TAVI)是介入心脏病学领域的一项重大变革,用于治疗有严重症状的主动脉瓣狭窄的老年或高风险外科手术患者。如今,TAVI似乎在治疗中度甚至可能是低风险的严重主动脉瓣狭窄患者中发挥着关键且可靠的作用。随着新一代设备的研发,TAVI也已从一项复杂且危险的手术演变为一种有效且安全的治疗方法。本文旨在回顾TAVI的背景与未来、使用新旧一代TAVI设备的临床试验和注册研究,并聚焦于一些与术后结果相关的未决问题。

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