Johnson Stoklossa Carlene A, Sharma Arya M, Forhan Mary, Siervo Mario, Padwal Raj S, Prado Carla M
Department of Agriculture, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada.
Department of Medicine, University of Alberta, Edmonton, AB, Canada.
J Nutr Metab. 2017;2017:7307618. doi: 10.1155/2017/7307618. Epub 2017 Mar 22.
. Sarcopenic obesity (SO) is a hidden condition of reduced lean soft tissue (LST) in context of excess adiposity. SO is most commonly reported in older adults and both its risk and prevalence increase with age. A variety of body composition indices and cut points have been used to define this condition, leading to conflicting prevalence and risk prediction. Here, we investigate variability in the prevalence of SO in an adult sample of individuals with class II/III obesity (BMI ≥ 35 kg/m) using different diagnostic criteria. . SO definitions were identified from a literature review of studies using dual-energy X-ray absorptiometry (DXA) to assess LST. Demographics, anthropometrics, and body composition (by DXA) were measured in = 120, 86% female (46.9 ± 11.1 years). . LST was extremely variable in individuals, even with similar body sizes, and observed across the age spectrum. The prevalence of SO ranged from 0 to 84.5% in females and 0 to 100% in males, depending upon the definition applied, with higher prevalence among definitions accounting for measures of body size or fat mass. . SO is present, yet variable, in adults with class II/III obesity. Accounting for body mass or fat mass may identify a higher number of individuals with SO, although risk prediction remains to be studied.
肌肉减少性肥胖(SO)是一种在肥胖情况下瘦软组织(LST)减少的隐匿性状况。SO在老年人中最为常见,其风险和患病率均随年龄增长而增加。多种身体成分指数和切点已被用于定义这种状况,导致患病率和风险预测相互矛盾。在此,我们使用不同的诊断标准,调查了II/III级肥胖(BMI≥35 kg/m²)成人样本中SO患病率的变异性。通过对使用双能X线吸收法(DXA)评估LST的研究进行文献综述来确定SO的定义。对120名个体(86%为女性,年龄46.9±11.1岁)进行了人口统计学、人体测量学和身体成分(通过DXA)测量。即使体型相似,个体的LST也存在极大差异,且在整个年龄范围内均有观察到。根据所应用的定义,女性SO的患病率在0至84.5%之间,男性在0至100%之间,考虑体型或脂肪量测量的定义中患病率更高。在II/III级肥胖的成年人中存在SO,但存在变异性。考虑体重或脂肪量可能会识别出更多的SO个体,尽管风险预测仍有待研究。