MYCL在人类中定位于1号染色体的确认及其相对于RH、UMPK和PGM1的位置。

Confirmation of the assignment of MYCL to chromosome 1 in humans and its position relative to RH, UMPK, and PGM1.

作者信息

Zelinski T, Verville G, White L, Hamerton J L, McAlpine P J, Lewis M

机构信息

Department of Pediatrics, Faculty of Medicine, University of Manitoba, Winnipeg, Canada.

出版信息

Genomics. 1988 Feb;2(2):154-6. doi: 10.1016/0888-7543(88)90097-3.

DOI:10.1016/0888-7543(88)90097-3

PMID:2842250

Abstract

Data from family studies demonstrating RH:MYCL linkage (zeta = 4.07 at theta = 0.09) in paternal meioses are presented. Although positive, MYCL:PGM1 lods are not of the magnitude of those for RH:MYCL. Taken together, these results are consistent with the physical assignment of MYCL to 1p32. Furthermore, evidence to support the order RH-MYCL-UMPK-PGM1 is detailed.

摘要

呈现了来自家族研究的数据，这些数据表明在父本减数分裂中存在RH:MYCL连锁（在θ = 0.09时ζ = 4.07）。尽管MYCL:PGM1的lod值为阳性，但并不如RH:MYCL的lod值那么大。综合来看，这些结果与将MYCL物理定位到1p32是一致的。此外，还详细阐述了支持RH-MYCL-UMPK-PGM1顺序的证据。