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胸椎后路椎体次全切除术中不融合的微创器械操作:经皮器械操作的非融合节段与开放器械操作的融合节段的比较

Minimally invasive instrumentation without fusion during posterior thoracic corpectomies: a comparison of percutaneously instrumented nonfused segments with open instrumented fused segments.

作者信息

Lau Darryl, Chou Dean

机构信息

Department of Neurological Surgery, University of California, San Francisco, California.

出版信息

J Neurosurg Spine. 2017 Jul;27(1):35-41. doi: 10.3171/2016.12.SPINE16598. Epub 2017 Apr 21.

Abstract

OBJECTIVE During the mini-open posterior corpectomy, percutaneous instrumentation without fusion is performed above and below the corpectomy level. In this study, the authors' goal was to compare the perioperative and long-term implant failure rates of patients who underwent nonfused percutaneous instrumentation with those of patients who underwent traditional open instrumented fusion. METHODS Adult patients who underwent posterior thoracic corpectomies with cage reconstruction between 2009 and 2014 were identified. Patients who underwent mini-open corpectomy had percutaneous instrumentation without fusion, and patients who underwent open corpectomy had instrumented fusion above and below the corpectomy site. The authors compared perioperative outcomes and rates of implant failure requiring reoperation between the open (fused) and mini-open (unfused) groups. RESULTS A total of 75 patients were identified, and 53 patients (32 open and 21 mini-open) were available for followup. The mean patient age was 52.8 years, and 56.6% of patients were male. There were no significant differences in baseline variables between the 2 groups. The overall perioperative complication rate was 15.1%, and there was no significant difference between the open and mini-open groups (18.8% vs 9.5%; p = 0.359). The mean hospital stay was 10.5 days. The open group required a significantly longer stay than the mini-open group (12.8 vs 7.1 days; p < 0.001). Overall implant failure rates requiring reoperation were 1.9% at 6 months, 9.1% at 1 year, and 14.7% at 2 years. There were no significant differences in reoperation rates between the open and mini-open groups at 6 months (3.1% vs 0.0%, p = 0.413), 1 year (10.7% vs 6.2%, p = 0.620), and 2 years (18.2% vs 8.3%, p = 0.438). The overall mean follow-up was 29.2 months. CONCLUSIONS These findings suggest that percutaneous instrumentation without fusion in mini-open transpedicular corpectomies offers similar implant failure and reoperation rates as open instrumented fusion as far out as 2 years of follow-up.

摘要

目的 在微创后路椎体次全切除术中,于椎体次全切除节段的上下方进行不融合的经皮器械固定。在本研究中,作者的目的是比较接受非融合经皮器械固定患者与接受传统开放器械融合患者的围手术期及长期内固定失败率。方法 确定2009年至2014年间接受后路胸椎椎体次全切除并进行椎间融合器重建的成年患者。接受微创椎体次全切除术的患者采用不融合的经皮器械固定,接受开放椎体次全切除术的患者在椎体次全切除部位的上下方进行器械融合。作者比较了开放(融合)组和微创(非融合)组的围手术期结果及需要再次手术的内固定失败率。结果 共确定75例患者,53例患者(32例开放手术和21例微创手术)可供随访。患者平均年龄为52.8岁,56.6%为男性。两组间基线变量无显著差异。总体围手术期并发症发生率为15.1%,开放组和微创组之间无显著差异(18.8%对9.5%;p = 0.359)。平均住院时间为10.5天。开放组的住院时间显著长于微创组(12.8天对7.1天;p < 0.001)。需要再次手术的总体内固定失败率在6个月时为1.9%,1年时为9.1%,2年时为14.7%。开放组和微创组在6个月(3.1%对0.0%,p = 0.413)、1年(10.7%对6.2%,p = 0.620)和2年(18.2%对8.3%,p = 0.438)时的再次手术率无显著差异。总体平均随访时间为29.2个月。结论 这些发现表明,在微创经椎弓根椎体次全切除术中不融合的经皮器械固定与开放器械融合相比,在长达2年的随访中具有相似的内固定失败率和再次手术率。

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