Department of Surgery, University of Calgary, Calgary, Alberta, Canada.
Department of Neurosurgery, Wooridul Hospital, Seoul, Korea.
Spine (Phila Pa 1976). 2017 Nov 15;42(22):1693-1698. doi: 10.1097/BRS.0000000000002209.
MINI: Proximal junctional kyphosis (PJK) is a common, yet incompletely understood, complication of surgery for adult spinal deformity. We analyzed 440 consecutive adult spinal deformity patients for trends in development of PJK and need for revision surgery. pelvic tilt and thoracic kyphosis were predictive for developing PJK, while radiographic evidence of proximal junctional failure was predictive for proceeding to revision.
Retrospective review of prospectively collected data.
The aim of this study was to examine which radiographic parameters and surgical strategies are most closely associated with proximal junctional kyphosis (PJK) after adult spinal deformity (ASD) surgery, the need for revision surgery for PJK, and whether these differ based on the upper instrumented vertebra (UIV).
Multiple parameters are considered when planning correction of ASD. Determining which of these factors contribute to the development of and need for revision surgery for PJK presents a challenging problem.
Consecutive patients undergoing long fusion to the pelvis with age >18 years, minimum 6-month follow-up, and adequate radiographs for analysis in a single institution between 2003 and 2011 were included. Along with chart review, measurement of proximal junctional angle (PJA), sagittal balance, and pelvic parameters was performed on preoperative, postoperative, and latest follow-up radiographs. Postoperative radiographs were also examined for signs of PJF.
A total of 440 patients with a mean follow-up of 34 months met inclusion criteria, 159 of whom developed PJK (36%), with 65 requiring revision surgery (41%). Higher preoperative pelvic tilt (PT) (P = 0.018) and postoperative thoracic kyphosis (TK) (P ≤ 0.001) were predictive for development of PJK, whereas hooks at UIV were protective (odds ratio [OR] 0.049). In patients who developed PJK, revision was more frequent in younger patients (P = 0.005) with greater postoperative sagittal vertical axis and PJA (P = 0.029, P = 0.018). PJF with spondylolisthesis, fracture, or instrumentation failure at the UIV had the highest ORs for proceeding to a revision (5.1, 1.6, and 2.2, respectively).
TK and PT are important indicators of overall rigidity and reference the ability of the spine to compensate for sagittal plane deformity. Special attention should be paid to these characteristics and to the choice of proximal instrumentation when attempting to prevent PJK. Prevention of radiographically evident PJF may hold the key to reducing the need for revision surgery.
本研究旨在探讨哪些影像学参数和手术策略与成人脊柱畸形(ASD)手术后近端交界性后凸(PJK)的发生、PJK 翻修手术的需要最为密切相关,以及这些因素是否因上固定椎(UIV)而异。
在规划 ASD 矫正时,会考虑多个参数。确定这些因素中的哪些因素导致 PJK 的发生和需要翻修手术,这是一个具有挑战性的问题。
本研究纳入了 2003 年至 2011 年期间在一家机构接受长节段融合至骨盆、年龄>18 岁、至少有 6 个月随访且影像学资料充足的连续患者。除了病历回顾外,还在术前、术后和最新随访的影像学检查中测量了近端交界角(PJA)、矢状面平衡和骨盆参数。术后影像学检查还观察了近端交界失败(PJF)的迹象。
共有 440 例患者符合纳入标准,平均随访 34 个月,其中 159 例(36%)发生 PJK,65 例(41%)需要翻修手术。较高的术前骨盆倾斜度(PT)(P = 0.018)和术后胸椎后凸(TK)(P ≤ 0.001)与 PJK 的发生相关,而 UIV 上使用钩则具有保护作用(比值比[OR] 0.049)。在发生 PJK 的患者中,年轻患者(P = 0.005)、术后矢状垂直轴和 PJA 较大的患者(P = 0.029,P = 0.018)翻修更为频繁。UIV 处的 PJF 伴滑脱、骨折或器械失败的患者,其进行翻修的比值比(OR)最高(分别为 5.1、1.6 和 2.2)。
TK 和 PT 是整体刚性的重要指标,反映了脊柱在补偿矢状面畸形方面的能力。在试图预防 PJK 时,应特别注意这些特征以及近端器械的选择。预防影像学上明显的 PJF 可能是减少翻修手术需要的关键。
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