精神分裂症患者的杏仁核灰质体积与社交关系
Amygdalar Gray Matter Volume and Social Relating in Schizophrenia.
作者信息
Günther Vivien, Lindner Christian, Dannlowski Udo, Kugel Harald, Suslow Thomas
机构信息
Department of Psychosomatic Medicine, University of Leipzig, Leipzig, Germany.
出版信息
Neuropsychobiology. 2016;74(3):139-143. doi: 10.1159/000458528. Epub 2017 Apr 26.
BACKGROUND
Poor social relating is a prominent feature of schizophrenia. The amygdala has been suggested as an important node in social brain networks.
METHODS
By using structural magnetic resonance imaging, this study examined, for the first time, the relationship between amygdalar gray matter (GM) volume and social relating in 35 schizophrenia patients. Social anhedonia, interaction anxiety, extraversion, and sociable tendencies were assessed as indices of social relating.
RESULTS
A correlation between GM volume in the amygdala and enhanced social relating was revealed.
CONCLUSION
These findings indicate that volumetric decreases in the amygdala are related to impoverished sociability in schizophrenia.
背景
社交关系不良是精神分裂症的一个突出特征。杏仁核被认为是社会脑网络中的一个重要节点。
方法
本研究首次使用结构磁共振成像，对35例精神分裂症患者杏仁核灰质（GM）体积与社交关系之间的关系进行了研究。社交快感缺失、互动焦虑、外向性和社交倾向被评估为社交关系的指标。
结果
发现杏仁核GM体积与增强的社交关系之间存在相关性。
结论
这些发现表明，杏仁核体积减小与精神分裂症患者社交能力低下有关。
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