结核性纤维胸和脓胸患者的肺癌：计算机断层扫描和18F-氟脱氧葡萄糖正电子发射断层扫描结果

Lung Cancer in Patients With Tuberculous Fibrothorax and Empyema: Computed Tomography and 18F-Fluorodeoxyglucose Positron Emission Tomography Findings.

作者信息

Xu Hai, Koo Hyun Jung, Lee Han Na, Lim Soyeoun, Lee Jae Wook, Choi Chang-Min, Kim Mi Young

机构信息

From the *Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea; †Department of Radiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China; and Departments of ‡Oncology and §Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

出版信息

J Comput Assist Tomogr. 2017 Sep/Oct;41(5):772-778. doi: 10.1097/RCT.0000000000000608.

DOI:10.1097/RCT.0000000000000608

PMID:28448410

Abstract

OBJECTIVE

The aim of this study was to describe the characteristics of lung cancers in patients with tuberculous fibrothorax or empyema.

METHODS

We retrospectively evaluated 138 consecutive patients with a diagnosis of lung cancer combined with fibrothorax (n = 127) or empyema (n = 11) from January 2005 to May 2015. All patients underwent computed tomography, and 105 underwent F-fluorodeoxyglucose positron emission tomography. Clinical, pathologic, and computed tomography characteristics and maximum standardized uptake values on positron emission tomography of 76 cancers ipsilateral to the fibrothorax or empyema (group 1) were compared with those of 62 contralateral cancers (group 2).

RESULTS

The median age at diagnosis of patients was 70 years, with a male-to-female ratio of 8.9:1. The most common type was squamous cell carcinoma (41.3%) followed by adenocarcinoma (39.1%). Most were in the peripheral lung (70.3%), and half abutted the pleura. The median maximum standardized uptake value was 8.9. Tumors in group 1 were larger (median, 48.5 vs 42.8 mm, P = 0.036) and more advanced (T3 or T4) (P = 0.014) than those in group 2.

CONCLUSIONS

Lung cancers ipsilateral to tuberculous fibrothorax or empyema presented larger and advanced T stages, and the diagnosis could be delayed. The most common type cancer was squamous cell carcinoma.

摘要

目的

本研究旨在描述结核性纤维胸或脓胸患者肺癌的特征。

方法

我们回顾性评估了2005年1月至2015年5月期间连续诊断为肺癌合并纤维胸（n = 127）或脓胸（n = 11）的138例患者。所有患者均接受了计算机断层扫描，105例接受了F-氟脱氧葡萄糖正电子发射断层扫描。将76例与纤维胸或脓胸同侧的癌症（第1组）的临床、病理和计算机断层扫描特征以及正电子发射断层扫描上的最大标准化摄取值与62例对侧癌症（第2组）进行比较。

结果

患者诊断时的中位年龄为70岁，男女比例为8.9:1。最常见的类型是鳞状细胞癌（41.3%），其次是腺癌（39.1%）。大多数位于肺外周（70.3%），半数与胸膜相邻。最大标准化摄取值的中位数为8.9。第1组的肿瘤比第2组的肿瘤更大（中位数，48.5对42.8 mm，P = 0.036）且分期更晚（T3或T4）（P = 0.014）。