Matsui Kentaro, Sasai-Sakuma Taeko, Ishigooka Jun, Inoue Yuichi
Department of Psychiatry, Tokyo Women's Medical University, Tokyo, Japan; Japan Somnology Center, Neuropsychiatric Research Institute, Tokyo, Japan.
Department of Somnology, Tokyo Medical University, Tokyo, Japan; Japan Somnology Center, Neuropsychiatric Research Institute, Tokyo, Japan; Department of Life Sciences and Bio-informatics, Division of Biomedical Laboratory Sciences, Graduate School of Health Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Sleep Med. 2017 May;33:19-22. doi: 10.1016/j.sleep.2016.07.022. Epub 2016 Sep 5.
Obstructive sleep apnea syndrome (OSAS) and insufficient sleep might increase the risk of drowsy driving and sleepiness-related vehicular accidents. This study retrospectively investigated the factors associated with these driving problems, particularly addressing OSAS severity and sleep amounts of affected drivers.
This study examined 161 patients (146 male and 15 female) with OSAS (apnea-hypopnea index [AHI] ≥ 5) who drove on a routine basis and who completed study questionnaires. To investigate factors associated with drowsy driving during the prior year and sleepiness-related vehicular accidents or near-miss events during the prior five years, logistic regression analyses were performed with age, body mass index, monthly driving distance, habitual sleep duration on weekdays, the Japanese version of Epworth Sleepiness Scale score, AHI, and periodic limb movement index as independent variables.
Of the patients, 68 (42.2%) reported drowsy driving experiences, and 86 (53.4%) reported sleepiness-related vehicular accidents or near-miss events. Analyses revealed the following: older age (46-65 years, ≥66 years) was negatively associated with drowsy driving (p <0.05, p <0.05), and habitually shorter sleep duration on weekdays (≤6 hours) was positively associated with drowsy driving (p <0.01). Habitual sleep duration of ≤6 hours (p <0.01) and Epworth Sleepiness Scale score of ≥11 (p <0.01) were positively associated with sleepiness-related vehicular accidents and near-miss events. However, AHI was not associated with these driving problems.
Insufficient sleep, rather than severity of OSAS, was associated with sleepiness-related driving problems in these Japanese OSAS patients.
阻塞性睡眠呼吸暂停综合征(OSAS)和睡眠不足可能会增加困倦驾驶以及与嗜睡相关的车辆事故风险。本研究回顾性调查了与这些驾驶问题相关的因素,尤其关注受影响驾驶员的OSAS严重程度和睡眠时长。
本研究对161例经常开车且完成研究问卷的OSAS患者(呼吸暂停低通气指数[AHI]≥5,其中男性146例,女性15例)进行了检查。为了调查与前一年困倦驾驶以及前五年与嗜睡相关的车辆事故或险些发生事故相关的因素,以年龄、体重指数、每月驾驶距离、平日习惯性睡眠时间、日语版爱泼沃斯嗜睡量表得分、AHI和周期性肢体运动指数作为自变量进行了逻辑回归分析。
在这些患者中,68例(42.2%)报告有困倦驾驶经历,86例(53.4%)报告有与嗜睡相关的车辆事故或险些发生事故。分析显示:年龄较大(46 - 65岁、≥66岁)与困倦驾驶呈负相关(p < 0.05,p < 0.05),平日习惯性睡眠时间较短(≤6小时)与困倦驾驶呈正相关(p < 0.01)。习惯性睡眠时间≤6小时(p < 0.01)和爱泼沃斯嗜睡量表得分≥11(p < 0.01)与与嗜睡相关的车辆事故和险些发生事故呈正相关。然而,AHI与这些驾驶问题无关。
在这些日本OSAS患者中,与嗜睡相关的驾驶问题与睡眠不足有关,而非OSAS的严重程度。