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一名接受抗肿瘤坏死因子治疗银屑病关节炎的患者发生严重腺型兔热病。

Severe glandular tularemia in a patient treated with anti-tumour necrosis factor for psoriatic arthritis.

作者信息

Calin Ruxandra, Caumes Eric, Reibel Florence, Ali Mohamed Anzime, Brossier Florence, Foltz Violaine, Boussouar Samia, Fautrel Bruno, Maurin Max, Katlama Christine, Pourcher Valérie

机构信息

Infectious and Tropical Diseases Department, Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris, Pierre et Marie Curie University, Paris, France.

Infectious and Tropical Diseases Department, Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris, Pierre et Marie Curie University, Paris, France.

出版信息

Int J Infect Dis. 2017 Jul;60:1-3. doi: 10.1016/j.ijid.2017.04.014. Epub 2017 Apr 24.

Abstract

A case of severe glandular tularemia in a patient receiving anti-tumour necrosis factor (TNF) therapy is reported here. The patient required prolonged treatment with doxycycline-ciprofloxacin due to early relapse after ciprofloxacin was stopped. Tularemia may have a more severe course in patients receiving anti-TNF. This may thus be an indication for more aggressive treatment.

摘要

本文报告了一例接受抗肿瘤坏死因子(TNF)治疗的患者发生严重腺型兔热病的病例。由于停用环丙沙星后早期复发,该患者需要接受多西环素-环丙沙星的长期治疗。接受抗TNF治疗的患者中兔热病病程可能更严重。因此,这可能是更积极治疗的一个指征。

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