Tsilimigras C W, Schoub B D
National Institute for Virology, University of the Witwatersrand Medical School, Johannesburg, Republic of South Africa.
J Infect. 1988 Sep;17(2):159-61. doi: 10.1016/s0163-4453(88)91795-1.
A clinical case of paralytic poliomyelitis with almost simultaneous isolation of two different types of poliovirus was investigated. A strain of poliovirus type I was isolated from the cerebrospinal fluid and a type 3 strain of poliovirus was isolated from the patient's faeces. Both strains were characterised by two-dimensional oligonucleotide mapping. The type I virus was shown to be of wild type while the type 3 virus was shown to be vaccine-associated.