Dams-OʼConnor Kristen, Mellick Dave, Dreer Laura E, Hammond Flora M, Hoffman Jeanne, Landau Alexandra, Zafonte Ross, Pretz Christopher
Department of Rehabilitation Medicine, Icahn School of Medicine at Mount Sinai, New York (Dr Dams-O'Connor and Ms Landau); Research Department, Craig Hospital, Englewood, Colorado (Mr Mellick and Dr Pretz); Departments of Physical Medicine and Rehabilitation and Ophthalmology, University of Alabama, Birmingham (Dr Dreer); Indiana University School of Medicine, Indianapolis (Dr Hammond); Department of Rehabilitation Medicine, University of Washington, Seattle (Dr Hoffman); and Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Massachusetts General Hospital, Brigham and Women's Hospital Harvard Medical School, Boston (Dr Zafonte).
J Head Trauma Rehabil. 2017 May/Jun;32(3):147-157. doi: 10.1097/HTR.0000000000000263.
To describe the rates and causes for rehospitalization over 10 years after moderate-severe traumatic brain injury (TBI), and to characterize longitudinal trajectories of the probability of rehospitalization using generalized linear mixed models and individual growth curve models conditioned on factors that help explain individual variability in rehospitalization risk over time.
Secondary analysis of data from a multicenter longitudinal cohort study.
Acute inpatient rehabilitation facilities and community follow-up.
Individuals 16 years and older with a primary diagnosis of TBI.
Rehospitalization (and reason for rehospitalization) as reported by participants or proxy during follow-up telephone interviews at 1, 2, 5, and 10 years postinjury.
The greatest number of rehospitalizations occurred in the first year postinjury (27.8% of the sample), and the rates of rehospitalization remained largely stable (22.1%-23.4%) at 2, 5, and 10 years. Reasons for rehospitalization varied over time: Orthopedic and reconstructive surgery rehospitalizations were most common in year 1, whereas general health maintenance was most common by year 2 with rates increasing at each follow-up. Longitudinal models indicate that multiple demographic and injury-related factors are associated with the probability of rehospitalization over time.
These findings can inform the content and timing of interventions to improve health and longevity after TBI.
描述中重度创伤性脑损伤(TBI)后10年的再住院率及原因,并使用广义线性混合模型和个体生长曲线模型,根据有助于解释再住院风险随时间变化的个体差异的因素,描述再住院概率的纵向轨迹。
对多中心纵向队列研究的数据进行二次分析。
急性住院康复机构和社区随访。
16岁及以上的原发性TBI诊断患者。
在受伤后1年、2年、5年和10年的随访电话访谈中,参与者或代理人报告的再住院情况(以及再住院原因)。
再住院人数最多发生在受伤后的第一年(占样本的27.8%),在2年、5年和10年时,再住院率基本保持稳定(22.1%-23.4%)。再住院原因随时间变化:骨科和重建手术再住院在第1年最为常见,而到第2年时,一般健康维护最为常见,且每次随访时的发生率都在增加。纵向模型表明,多种人口统计学和损伤相关因素与随时间推移的再住院概率相关。
这些发现可为改善TBI后健康和寿命的干预措施的内容和时机提供参考。