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艾瑞布林迅速降低第二原发性乳腺癌的侵袭性:一例病例报告。

Eribulin rapidly reduces the aggressiveness of second primary breast cancer: a case report.

作者信息

Falco Isacco, Stragliotto Silvia

机构信息

Oncologia, Ospedale di San Bassiano, ULSS no. 3 Bassano del Grappa, Vicenza, Italy.

Oncologia, IOV Istituto Oncologico Veneto, Padova, Italy.

出版信息

Future Oncol. 2017 Apr;13(11s):51-54. doi: 10.2217/fon-2016-0563.

Abstract

The cytotoxic agent, eribulin represents a new standard of care in the treatment of heavily pretreated metastatic breast cancer patients. Here, we describe our experience with eribulin in a patient with a controlled primary breast cancer, who showed an aggressive recurrence of the primary tumor, including metastatic disease. Treatment management of the second primary tumor included six lines of chemotherapy and three lines of hormonal therapy, including eribulin as sixth line among all chemotherapies received. Eribulin treatment achieved a fast response to all metastatic sites and decelerated the aggressive evolution of the second disease.

摘要

细胞毒性药物艾瑞布林是治疗经过多次治疗的转移性乳腺癌患者的一种新的治疗标准。在此,我们描述了一名原发性乳腺癌得到控制的患者使用艾瑞布林的经历,该患者出现了原发性肿瘤的侵袭性复发,包括转移性疾病。对第二原发性肿瘤的治疗管理包括六线化疗和三线激素治疗,在所有接受的化疗中,艾瑞布林作为第六线治疗药物。艾瑞布林治疗对所有转移部位均取得了快速反应,并减缓了第二种疾病的侵袭性进展。

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