Department of Neurology, Brain Tumour Centre, University Hospital and University of Zurich, Zurich, Switzerland.
Neurooncology Unit, Erasmus MC Cancer Institute, Rotterdam, Netherlands.
Lancet Oncol. 2017 Jun;18(6):e315-e329. doi: 10.1016/S1470-2045(17)30194-8. Epub 2017 May 5.
The European Association for Neuro-Oncology guideline provides recommendations for the clinical care of adult patients with astrocytic and oligodendroglial gliomas, including glioblastomas. The guideline is based on the 2016 WHO classification of tumours of the central nervous system and on scientific developments since the 2014 guideline. The recommendations focus on pathological and radiological diagnostics, and the main treatment modalities of surgery, radiotherapy, and pharmacotherapy. In this guideline we have also integrated the results from contemporary clinical trials that have changed clinical practice. The guideline aims to provide guidance for diagnostic and management decisions, while limiting unnecessary treatments and costs. The recommendations are a resource for professionals involved in the management of patients with glioma, for patients and caregivers, and for health-care providers in Europe. The implementation of this guideline requires multidisciplinary structures of care, and defined processes of diagnosis and treatment.
欧洲神经肿瘤学会指南为成人星形细胞瘤和少突胶质细胞瘤(包括胶质母细胞瘤)患者的临床护理提供了建议。该指南基于 2016 年世界卫生组织中枢神经系统肿瘤分类和自 2014 年指南以来的科学发展。建议侧重于病理和放射学诊断以及手术、放疗和药物治疗的主要治疗方式。在本指南中,我们还整合了改变临床实践的当代临床试验结果。本指南旨在为诊断和管理决策提供指导,同时限制不必要的治疗和费用。这些建议为参与胶质瘤患者管理的专业人员、患者及其护理人员以及欧洲的医疗保健提供者提供了资源。本指南的实施需要多学科的护理结构和明确的诊断和治疗流程。