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二尖瓣心内膜炎的微创外科手术

Minimal access surgery for mitral valve endocarditis.

作者信息

Barbero Cristina, Marchetto Giovanni, Ricci Davide, Mancuso Samuel, Boffini Massimo, Cecchi Enrico, De Rosa Francesco Giuseppe, Rinaldi Mauro

机构信息

Department of Cardiovascular and Thoracic Surgery, University of Torino, Città della Salute e della Scienza-San Giovanni Battista Hospital 'Molinette', Torino, Italy.

Department of Cardiology, Maria Vittoria Hospital, Torino, Italy.

出版信息

Interact Cardiovasc Thorac Surg. 2017 Aug 1;25(2):241-245. doi: 10.1093/icvts/ivx088.

Abstract

OBJECTIVES

Minimal access mitral valve surgery (MVS) has already proved to be feasible and effective with low perioperative mortality and excellent long-term outcomes. However, experience in more complex valve diseases such as infective endocarditis (IE) still remains limited. The aim of this retrospective study was to evaluate early and long-term results of minimal access MVS for IE.

METHODS

Data were entered into a dedicated database. Analysis was performed retrospectively for the 8-year period between January 2007 and April 2015.

RESULTS

During the study period, 35 consecutive patients underwent minimal access MVS for IE at our department. Twenty-four had diagnosis of native MV endocarditis (68.6%) and 11 of mitral prosthesis endocarditis (31.4%).Thirty patients underwent early MVS (85.7%), and 5 patients were operated after the completion of antibiotic treatment (14.3%). Seven patients underwent MV repair (20%), 17 patients underwent MV replacement (48.6%), and 11 patients underwent mitral prosthesis replacement (31.4%). Thirty-day mortality was 11.4% (4 patients). No neurological or vascular complications were reported. One patient underwent reoperation for prosthesis IE relapse after 37 days. Overall actuarial survival rate at 1 and 5 years was 83%; freedom from MV reoperation and/or recurrence of IE at 1 and 5 years was 97%.

CONCLUSIONS

Minimally invasive MVS for IE is feasible and associated with good early and long-term results. Preoperative accurate patient selection and transoesophageal echocardiography evaluation is mandatory for surgical planning.

摘要

目的

微创二尖瓣手术(MVS)已被证明是可行且有效的,围手术期死亡率低,长期效果良好。然而,在感染性心内膜炎(IE)等更复杂的瓣膜疾病方面的经验仍然有限。这项回顾性研究的目的是评估微创MVS治疗IE的早期和长期结果。

方法

数据录入专用数据库。对2007年1月至2015年4月的8年期间进行回顾性分析。

结果

在研究期间,我们科室连续35例患者接受了微创MVS治疗IE。24例诊断为原发性二尖瓣心内膜炎(68.6%),11例为二尖瓣人工瓣膜心内膜炎(31.4%)。30例患者接受了早期MVS(85.7%),5例患者在完成抗生素治疗后接受手术(14.3%)。7例患者接受二尖瓣修复(20%),17例患者接受二尖瓣置换(48.6%),11例患者接受二尖瓣人工瓣膜置换(31.4%)。30天死亡率为11.4%(4例)。未报告神经或血管并发症。1例患者在37天后因人工瓣膜IE复发接受再次手术。1年和5年的总体精算生存率为83%;1年和5年无二尖瓣再次手术和/或IE复发的概率为97%。

结论

微创MVS治疗IE是可行的,且早期和长期效果良好。术前准确的患者选择和经食管超声心动图评估对于手术规划至关重要。

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