A novel metal-free method for the selenocyanation of aromatic ketones to afford α-carbonyl selenocyanates.
作者信息
Sun Kai, Lv Yunhe, Chen Yao, Zhou Tingting, Xing Yanyan, Wang Xin
机构信息
College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, P. R. China.
出版信息
Org Biomol Chem. 2017 May 23;15(20):4464-4467. doi: 10.1039/c7ob00958e.
PMID:28489107
Abstract
A new method has been developed for the selenocyanation of aromatic ketones. This reaction avoids the need to use pre-prepared α-halo ketones, providing rapid access to α-carbonyl selenocyanates. We also investigated the mechanism for this reaction and found that it proceeds via sequential radical iodination and nucleophilic substitution reactions.
摘要
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