Lee Young, Park Mina
Department of Otorhinolaryngology-Head and Neck Surgery, Healthcare Research Institute, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea.
Department of Translational Biomedical Research, Seoul National University College of Medicine, Seoul, Korea.
Clin Exp Otorhinolaryngol. 2017 Dec;10(4):309-314. doi: 10.21053/ceo.2017.00017. Epub 2017 May 11.
Metabolic syndrome is related with abdominal fat and with age-related hearing loss (ARHL). In this study, we evaluated the association between a variety of factors relevant to abdominal fat (FRAs) and hearing thresholds.
We reviewed retrospectively the medical records of 2,602 subjects aged over 40 years with symmetrical sensorineural hearing loss who underwent abdominal fat computed tomography (CT) scans. Univariate and multivariate linear regression analyses were used to demonstrate the association between each FRA and hearing thresholds at low and high frequencies.
Four of 5 FRAs were associated with hearing thresholds at high frequencies in males. All FRAs examined showed a relationship with hearing thresholds at low frequencies in females. Diabetes mellitus (DM) among clinical factors and visceral adipose tissue (VAT) among the 5 FRAs were the most reflective of hearing thresholds in both males and females.
We found that FRAs were associated with hearing loss with frequency specific characteristics according to sex and reinforced that DM and VAT is particularly an important role for hearing.
代谢综合征与腹部脂肪以及年龄相关性听力损失（ARHL）有关。在本研究中，我们评估了多种与腹部脂肪相关的因素（FRAs）和听力阈值之间的关联。
我们回顾性分析了2602名40岁以上对称性感音神经性听力损失患者的病历，这些患者均接受了腹部脂肪计算机断层扫描（CT）。单因素和多因素线性回归分析用于证明各FRA与低频和高频听力阈值之间的关联。
5种FRA中的4种与男性高频听力阈值相关。所有检测的FRA均显示与女性低频听力阈值有关。临床因素中的糖尿病（DM）以及5种FRA中的内脏脂肪组织（VAT）在男性和女性中对听力阈值的反映最为明显。
我们发现FRA与听力损失有关，且根据性别具有频率特异性特征，并强调DM和VAT对听力尤其起着重要作用。
