Chen W Q, Zhang G H, Lin H J, Huang H C, Lin D S, Zheng J L, Zheng D Z
Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou 515041, China.
Zhonghua Yan Ke Za Zhi. 2017 May 11;53(5):332-337. doi: 10.3760/cma.j.issn.0412-4081.2017.05.004.
To investigate the visual impact and influence factors of sub-Tenons anesthesia in retinal detachment patients during pars plana vitrectomy (PPV) or combined phacoemulsification and PPV surgery. In this prospective case series study, 104 consecutive patients who underwent PPV or combined phacoemulsification and PPV under sub-Tenons anesthesia between October 2012 and December 2013 were enrolled. Intraoperatively, the patients were asked whether they could see the light of the operating microscope or not at 5 minutes after sub-Tenons anesthesia, and at the end of phacoemulsification, core vitreous removal, peripheral vitreous removal and the whole surgery, with their contralateral eyes being covered tightly and no photobleaching. The best corrected visual acuity and visual evoked potentials were examined and compared with each other preoperatively and at 1.5 months and 3 months postoperatively. Chi-square test was used to compare the detection rate of amaurosis between different modus operandi and whether covered contra-lateral eye. Student- test was used to compare the difference of age and preoperative BCVA between the patients with or without experienced amaurois. Lastly, BCVA between different times were tested by one-way analysis. Without covering the contralateral eyes, the incidence of no light perception in various surgical steps was 0%, while it was 72.1%(75/104), 93.8%(75/80), 96.2%(100/104), 96.2%(100/104) and 86.5%(90/104) at the five timepoints, respectively, when the contralateral eyes were covered tightly. The incidence was 51.9%(54/104), 85.0%(68/80), 85. 6%(89/104), 84.6%(69/104) and 66.3%(88/104), respectively, after photobleaching was excluded. Approximately 95.2%(99/104) of patients reported no light perception at least once, 54.5%(54/99) reported no light perception 5 minutes after sub-Tenons anesthesia, and 30.3%(30/99) recovered light perception when the surgery was finished. All eyes recovered to at least light perception on the first postoperative day. The best corrected visual acuity and visual evoked potentials at 1.5 months and 3 months postoperatively were significantly better than those before surgery. The BCVA was 1.75±0.78 preoperative, 0.96±0.63 1.5 months after operation, and 0.92±0.57 3 months after operation. There was a significant statistical difference between preoperative BCVA and postoperative BCVA (50.61, 0.01) . In patients without waveform detection preoperatively, PVEP waveform could be found in 43.6% and 61.4% of the pactients at 1.5 months and 3 months after operation respectively. In those had certain waveform preoperatively, PVEP amplitudes rise significantly after surgery ((1.5)=-2.69, (3)=-2.97, 0.05) . No light perception was detected in various surgical steps of vitrectomy under sub-Tenons anesthesia in most patients. The blocking of optic nerve conduction may be caused by sub-Tenon s anesthesia. Photobleaching can also have some effect. The incidence of no light perception during the surgery was not correlated with preoperative visual acuity, age and gender. Moreover, the effect was transient and harmless to visual function.-.
探讨视网膜脱离患者在玻璃体切割术(PPV)或联合超声乳化和PPV手术中球后麻醉的视觉影响及影响因素。在这项前瞻性病例系列研究中,纳入了2012年10月至2013年12月期间连续104例行球后麻醉下PPV或联合超声乳化和PPV的患者。术中,在球后麻醉5分钟后、超声乳化结束时、核心玻璃体切除时、周边玻璃体切除时及手术结束时,询问患者是否能看到手术显微镜的灯光,对侧眼紧密遮盖且无光漂白。术前、术后1.5个月和3个月检查并比较最佳矫正视力和视觉诱发电位。采用卡方检验比较不同手术方式及是否遮盖对侧眼时黑矇的检出率。采用t检验比较有或无黑矇经历患者的年龄和术前最佳矫正视力差异。最后,采用单因素分析比较不同时间的最佳矫正视力。未遮盖对侧眼时,各手术步骤无光感发生率为0%,而紧密遮盖对侧眼时,在五个时间点的发生率分别为72.1%(75/104)、93.8%(75/80)、96.2%(100/104)、96.2%(100/104)和86.5%(90/104)。排除光漂白后,发生率分别为51.9%(54/104)、85.0%(68/80)、85.6%(89/104)、84.6%(69/104)和66.3%(88/104)。约95.2%(99/104)的患者至少有一次无光感报告,54.5%(54/99)在球后麻醉5分钟后无光感报告,30.3%(30/99)在手术结束时恢复光感。所有患眼术后第一天均恢复至至少光感。术后1.5个月和3个月的最佳矫正视力和视觉诱发电位明显优于术前。术前最佳矫正视力为1.75±0.78,术后1.5个月为0.96±0.63,术后3个月为0.92±0.57。术前与术后最佳矫正视力有显著统计学差异(χ²=50.61,P=0.01)。术前无波形检测的患者,术后1.5个月和3个月分别有43.6%和61.4%可检测到PVEP波形。术前有一定波形的患者,术后PVEP波幅明显升高(t(1.5)=-2.69,t(3)=-2.97,P<0.05)。大多数患者在球后麻醉下玻璃体切除的各手术步骤中均检测到无光感。球后麻醉可能导致视神经传导阻滞。光漂白也有一定影响。手术中无光感发生率与术前视力、年龄和性别无关。此外,这种影响是短暂的,对视觉功能无害。