Division of Cardiovascular Medicine, Department of Medicine, China Medical University Hospital.
Cardiovascular Research Laboratory, China Medical University Hospital.
Circ J. 2017 Sep 25;81(10):1419-1423. doi: 10.1253/circj.CJ-16-1308. Epub 2017 May 11.
Refractory pulmonary edema is an infrequent but serious complication in patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO) for myocardial failure. Left atrial (LA) decompression in this setting is important. Although a few methods have been reported, the experience is mostly limited to children. We aimed to evaluate the feasibility of Inoue balloon catheter in percutaneous trans-septal LA decompression in adult cardiogenic patients.Methods and Results:We retrospectively analyzed 16 procedures of trans-septal LA decompression by Inoue balloon catheter in 15 VA-ECMO patients (aged 22-65 years, 6 men) with refractory pulmonary edema from May 2012 to December 2014. Mean left ventricular ejection fraction was 15%. The cause of cardiogenic shock included 7 cases of ischemic heart disease, 1 of dilated cardiomyopathy, 5 of myocarditis, and 2 of fatal ventricular arrhythmia.The procedures were performed 4.3 days after ECMO. Inoue balloon size was 24-27 mm. LA septostomy were successfully created in 14 patients. Procedure time on average was 36.8 min (range, 15-85 min). There were no procedure-related complications.Radiography on the next day showed rapid resolution of pulmonary edema.
Trans-septal LA decompression by Inoue balloon catheter is a feasible alternative method for adult patients with refractory pulmonary edema under ECMO.
在接受静脉-动脉体外膜肺氧合(VA-ECMO)治疗心肌衰竭的患者中,难治性肺水肿是一种罕见但严重的并发症。在此情况下,左心房(LA)减压很重要。尽管已经报道了几种方法,但经验主要限于儿童。我们旨在评估 Inoue 球囊导管在成人心源性病理性肺水肿患者经皮经房间隔 LA 减压中的可行性。
我们回顾性分析了 2012 年 5 月至 2014 年 12 月期间 15 例接受 VA-ECMO 的难治性肺水肿患者(年龄 22-65 岁,男性 6 例)中 16 例经 Inoue 球囊导管进行经房间隔 LA 减压的手术。平均左心室射血分数为 15%。心源性休克的病因包括缺血性心脏病 7 例、扩张型心肌病 1 例、心肌炎 5 例、致命性室性心律失常 2 例。该手术在 ECMO 后 4.3 天进行。Inoue 球囊大小为 24-27mm。14 例患者成功进行了 LA 房间隔切开术。平均手术时间为 36.8 分钟(范围 15-85 分钟)。无手术相关并发症。次日的 X 光片显示肺水肿迅速缓解。
对于 ECMO 下难治性肺水肿的成年患者,经 Inoue 球囊导管进行经房间隔 LA 减压是一种可行的替代方法。