Gomes Md Sophie, Champ-Rigot Md Laure, Foucault Md Anthony, Arnaud Pellissier Md, Lebon Md Alain, Scanu Md Patrice, Milliez Md PhD Paul
Cardiology Department, Caen University Hospital, Normandy, France.
J Atr Fibrillation. 2012 Apr 14;4(6):403. doi: 10.4022/jafib.403. eCollection 2012 Apr-May.
Atrial fibrillation (AF) is the most frequent supraventricular arrhythmia with an approximative prevalence of 1 % in the general population and above 6 % in the elderly. After a first AF diagnosis, the hospitalization rate is markedly increased. Management of a first AF episode is different depending on the clinical status of patients. Practical guidelines developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society are available for the management of these patients. A four-step decisional scheme must be followed in the management of a first recent AF episode: need for a short- and long-term anticoagulation, define a rythmologic strategy (rhythm or rate control), select the weapon (drug, device or ablation) and reconsider the strategy if needed. After a first uncomplicated paroxysmal AF episode, guidelines recommend that prescription of antiarrhythmics must be avoided and anticoagulation is optional. After a first persistent AF episode, guidelines recommend to either respect or reduce the arrhythmia. Prescription of antiarrhythmics and anticoagulation is also optional depending on the patient?s condition. In case of the AF reduction decision, anticoagulation must be tailored preliminary to this reduction. AF recurrence rate varies depending on the patient?s condition, and the risk of stroke assessed by the CHADS-VASc score might be similarly considered for both paroxysmal and persistent AF.
心房颤动(AF)是最常见的室上性心律失常,在普通人群中的患病率约为1%,在老年人中则超过6%。首次诊断为房颤后,住院率会显著增加。首次房颤发作的管理因患者的临床状况而异。与欧洲心律协会和心律学会合作制定的实用指南可用于这些患者的管理。在管理首次近期房颤发作时,必须遵循一个四步决策方案:短期和长期抗凝的必要性、确定节律控制策略(节律或心率控制)、选择治疗手段(药物、器械或消融),并在需要时重新考虑策略。在首次无并发症的阵发性房颤发作后,指南建议避免使用抗心律失常药物,抗凝治疗为可选。在首次持续性房颤发作后,指南建议要么控制心律失常,要么减少心律失常发作。根据患者情况,抗心律失常药物和抗凝治疗也为可选。在决定减少房颤发作的情况下,必须在减少发作之前调整抗凝治疗。房颤复发率因患者情况而异,对于阵发性和持续性房颤,通过CHADS-VASc评分评估的中风风险可能同样需要考虑。