Dewire Jane, Calkins Hugh
Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
J Atr Fibrillation. 2013 Feb 12;5(5):777. doi: 10.4022/jafib.777. eCollection 2013 Feb-Mar.
Obstructive sleep apnea (OSA) is a growing epidemic in the United States and significantly contributes to the increasing prevalence of atrial fibrillation (AF) in the U.S.
Although a strong correlation between OSA and AF has been demonstrated, a causal relationship between these two conditions has not been definitively established. Evidence of OSA is an important consideration of AF management and impacts the success rate of catheter ablation. The presence of OSA tends to predict a lower success rate and higher complication rate for catheter ablation of AF. However, recent studies evaluating OSA as an independent risk predictor of AF recurrence following an ablation procedure have yielded conflicting results. A greater understanding of these conditions would allow for a more specific therapy targeting the type of AF associated with OSA. The following review provides a brief summary of obstructive sleep apnea etiology, focuses on the relationship between OSA and AF, and discusses the impact of OSA on the outcomes of catheter ablation of AF.
阻塞性睡眠呼吸暂停(OSA)在美国是一种日益流行的疾病,并且对美国心房颤动(AF)患病率的上升有显著影响。
尽管已证实OSA与AF之间存在密切关联,但这两种疾病之间的因果关系尚未明确确立。OSA的证据是AF管理的重要考虑因素,并影响导管消融的成功率。OSA的存在往往预示着AF导管消融的成功率较低且并发症发生率较高。然而,最近评估OSA作为消融术后AF复发的独立风险预测因素的研究结果相互矛盾。对这些疾病有更深入的了解将有助于针对与OSA相关的AF类型进行更具针对性的治疗。以下综述简要总结了阻塞性睡眠呼吸暂停的病因,重点关注OSA与AF之间的关系,并讨论了OSA对AF导管消融结果的影响。