Shah Ashok J, Hocini Meleze, Komatsu Yuki, Daly Matthew, Zellerhoff Stephan, Jesel Laurence, Amaroui Sana, Ramoul Khaled, Denis Arnaud, Derval Nicolas, Sacher Frederic, Jais Pierre, Haissaguerre Michel
Hôpital Cardiologique du Haut-Lévêque and the Université Bordeaux II, Bordeaux, France.
J Atr Fibrillation. 2013 Aug 31;6(2):849. doi: 10.4022/jafib.849. eCollection 2013 Aug-Sep.
Atrial fibrillation (AF) is the manifest outcome of a multifactorial, progressive disease process,secondarily or primarily involving the atrial chambers. The slowly progressive electrostructural alterations diffusely involve the atrial substrate and lead to persistent and permanent forms of AF. Although the progression of the AF disease process is variable and associated with the development of comorbid conditions, rhythm restoration therapies, particularly catheter ablation,provide higher acute and long-term success rates in paroxysmal than non-paroxysmal AF. This review of literature aims to discuss how early restoration and maintenance of sinus rhythm especially using novel approaches can influence the progressive nature of atrial fibrillation.
心房颤动（AF）是一种多因素、进行性疾病过程的明显结果，其次要或主要累及心房腔室。缓慢进展的电结构改变广泛累及心房基质，并导致持续性和永久性房颤。尽管房颤疾病过程的进展具有变异性，且与合并症的发生相关，但节律恢复疗法，尤其是导管消融，对阵发性房颤的急性和长期成功率高于非阵发性房颤。这篇文献综述旨在探讨窦性心律的早期恢复和维持，尤其是采用新方法，如何影响心房颤动的进展特性。
