Department of Family & Community Medicine, San Francisco, USA.
Behavioral Diabetes Institute, San Francisco, USA.
Diabet Med. 2017 Sep;34(9):1228-1234. doi: 10.1111/dme.13381. Epub 2017 Jun 18.
To determine the cross-sectional and longitudinal associations between diabetes distress and diabetes management.
In a non-interventional study, 224 adults with Type 1 diabetes were assessed for diabetes distress, missed insulin boluses, hypoglycaemic episodes, and HbA at baseline and 9 months.
At baseline, greater distress was associated with higher HbA and a greater percentage of missed insulin boluses. Longitudinally, elevated baseline distress was related to increased missed insulin boluses, and decreases in distress were associated with decreases in HbA . In supplementary analyses, neither depression symptoms nor a diagnosis of major depressive disorder was associated with missed insulin boluses, HbA or hypoglycaemic episodes in cross-sectional or longitudinal analyses.
Significant cross-sectional and longitudinal associations were found between diabetes distress and management; in contrast, no parallel associations were found for major depressive disorder or depression symptoms. Findings suggest that elevated distress may lead to more missed insulin boluses over time, suggesting a potential intervention target. The covarying association between distress and HbA points to the complex and likely interactive associations between these constructs. Findings highlight the need to address distress as an integral part of diabetes management in routine care.
确定糖尿病困扰与糖尿病管理之间的横断面和纵向关联。
在一项非干预性研究中,对 224 名 1 型糖尿病患者进行了糖尿病困扰、漏注胰岛素、低血糖发作和 HbA1c 的基线和 9 个月评估。
基线时,较高的困扰与较高的 HbA1c 和更多的胰岛素漏注有关。纵向分析显示,较高的基线困扰与更多的胰岛素漏注有关,而困扰程度的降低与 HbA1c 的降低有关。在补充分析中,在横断面或纵向分析中,抑郁症状或重度抑郁障碍的诊断均与漏注胰岛素、HbA1c 或低血糖发作无关。
在糖尿病困扰和管理之间发现了显著的横断面和纵向关联;相比之下,在重度抑郁障碍或抑郁症状方面没有发现平行关联。研究结果表明,随着时间的推移,较高的困扰可能会导致更多的胰岛素漏注,这表明困扰可能是一个潜在的干预靶点。困扰和 HbA 之间的共变关系表明,这些结构之间存在复杂的、可能相互作用的关联。研究结果强调了在常规护理中,需要将困扰作为糖尿病管理的一个组成部分来解决。