在酿酒酵母中，两种不同的蛋白激酶活性可使Ras2蛋白磷酸化。

Two different protein kinase activities phosphorylate Ras2 protein in Saccharomyces cerevisiae.

作者信息

Sreenath T L, Breviario D, Ahmed N, Dhar R

机构信息

Laboratory of Molecular Virology, National Cancer Institute, Bethesda, MD 20892.

出版信息

Biochem Biophys Res Commun. 1988 Dec 30;157(3):1182-9. doi: 10.1016/s0006-291x(88)80999-9.

DOI:10.1016/s0006-291x(88)80999-9

PMID:2849931

Abstract

In this report, we show that Ras2 protein in the yeast Saccharomyces cerevisiae is phosphorylated in vivo by protein kinase(s) and the phosphorylation is stable. Ras2 protein is phosphorylated by cAMP dependent protein kinase and by an additional protein kinase activity which is independent of cAMP levels.

摘要

在本报告中，我们表明酿酒酵母中的Ras2蛋白在体内被蛋白激酶磷酸化，且这种磷酸化是稳定的。Ras2蛋白被环磷酸腺苷（cAMP）依赖性蛋白激酶以及一种独立于cAMP水平的额外蛋白激酶活性磷酸化。