Wagenaar Nienke, van der Aa Niek E, Groenendaal Floris, Verhage Cornelia H, Benders Manon J N L, de Vries Linda S
Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, The Netherlands; Brain Center Rudolf Magnus, University Medical Center Utrecht, The Netherlands.
Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, The Netherlands.
Eur J Paediatr Neurol. 2017 Jul;21(4):666-670. doi: 10.1016/j.ejpn.2017.04.002. Epub 2017 Apr 12.
Involvement of the corticospinal tracts after perinatal arterial ischemic stroke (PAIS) is strongly correlated with adverse motor outcome.
Two full-term infants with PAIS, with two early MRI scans available, are reported.
Diffusion weighted imaging (DWI)-MRI, performed within 24 h following onset of seizures and repeated 48 h later, clearly showed restricted diffusion within the middle cerebral artery territory on both MRIs, but clear patterns of signal intensity changes in the descending corticospinal tracts on the second MRI only.
Since involvement of the corticospinal tracts is essential for prediction of motor outcome, we may need to reconsider optimal timing of MR imaging for prediction of neurodevelopmental outcome after PAIS.
围产期动脉缺血性卒中（PAIS）后皮质脊髓束受累与不良运动结局密切相关。
报告了两名患有PAIS的足月儿，他们有两次早期MRI扫描结果。
在癫痫发作后24小时内进行的扩散加权成像（DWI）-MRI检查，并在48小时后重复检查，两次MRI均清楚显示大脑中动脉区域内扩散受限，但仅在第二次MRI上显示皮质脊髓束下行信号强度变化的清晰模式。
由于皮质脊髓束受累对运动结局的预测至关重要，我们可能需要重新考虑PAIS后神经发育结局预测的MRI最佳检查时机。
