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膀胱结石对脊髓损伤患者下尿路动力学的影响。

Influence of bladder lithiasis on lower urinary tract dynamics in patients with spinal cord injury.

作者信息

Vírseda-Chamorro M, Salinas-Casado J, Barroso-Manso Á, Gutiérrez-Martín P, Fuertes M E

机构信息

Urology Department, Hospital Nacional de Parapléjicos, Toledo, Spain.

Urology Department, Hospital Clínico de San Carlos, Complutense University, Madrid, Spain.

出版信息

Spinal Cord. 2017 Aug;55(8):765-768. doi: 10.1038/sc.2017.46. Epub 2017 May 16.

Abstract

STUDY DESIGN

A prospective and a case-matched control study.

OBJECTIVES

To study the lower urinary tract dysfunction associated with bladder lithiasis in patients with spinal cord injury (SCI).

SETTING

Toledo (Spain).

METHODS

We have carried out a urodynamic study in 30 patients with SCI with lithiasis in their bladder before and 3 months after bladder endoscopic lithotripsy. This second study was compared with the urodynamic findings of a different group of 30 patients with SCI, without a history of bladder lithiasis, paired with cases by gender and date of urodynamic study.

RESULTS

We have found that the prevalence of neurogenic detrusor overactivity (NDO) was significantly different after bladder lithotripsy, although the cystomanometric capacity was significantly increased. A group of patients with lithiasis showed a maximum flow rate, a voiding maximum detrusor pressure and the detrusor contractility parameter Wmax lower than that in controls. On the other hand, a voiding abdominal straining was found to be significantly greater than that in controls.

CONCLUSIONS

Bladder lithiasis affects the presence of NDO in patients with SCI. Patients with SCI who develop bladder lithiasis present a lower detrusor contractility power compared with those who do not.

摘要

研究设计

一项前瞻性病例对照研究。

目的

研究脊髓损伤(SCI)患者中与膀胱结石相关的下尿路功能障碍。

地点

西班牙托莱多。

方法

我们对30例膀胱有结石的SCI患者在膀胱内镜碎石术前及术后3个月进行了尿动力学研究。将第二项研究与另一组30例无膀胱结石病史的SCI患者的尿动力学结果进行比较,这组患者按性别和尿动力学研究日期与病例配对。

结果

我们发现,尽管膀胱测压容量显著增加,但膀胱碎石术后神经源性逼尿肌过度活动(NDO)的患病率有显著差异。一组有结石的患者的最大尿流率、排尿时最大逼尿肌压力和逼尿肌收缩力参数Wmax低于对照组。另一方面,发现排尿时腹部用力明显大于对照组。

结论

膀胱结石影响SCI患者NDO的存在。与未发生膀胱结石的SCI患者相比,发生膀胱结石的SCI患者逼尿肌收缩力较低。

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