On November 17, 2016, the Roundtable on Health Literacy of the National Academies of Sciences, Engineering, and Medicine convened a workshop on communicating clearly about medicines. The workshop focused on the clarity of written information given to patients and consumers as printed or digital materials. Participants explored the design of health-literate written materials and examples that illustrated implementation of research into the development of these materials. This publication summarizes the presentations and discussions from the workshop.