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利用伽马射线辐照使烟草花叶病毒失活及其潜在作用模式。

Inactivation of tobacco mosaic virus using gamma irradiation and its potential modes of action.

作者信息

Jeong R-D, Choi H-S

出版信息

Acta Virol. 2017;61(2):223-225. doi: 10.4149/av_2017_02_14.

DOI:10.4149/av_2017_02_14
PMID:28523930
Abstract

Gamma irradiation is a non-thermal processing technique used to disinfect harmful microorganisms in agriculture. This technology has been shown to be an effective method to control bacterial and fungal plant pathogens. However, its effect on viral plant pathogen is less understood. Gamma irradiation was evaluated for the inactivation of tobacco mosaic virus (TMV). TMV infectivity has gradually decreased following irradiation in a dose-dependent manner and virus was completely inactivated at a dose over 40 kGy. Transmission electron microscopy revealed that increased gamma irradiation disrupts the virion structure and degrades viral proteins, which results in TMV inactivation. The mechanisms, through which gamma irradiation inactivates TMV, can be directly associated with the damage to the virus constituents.

摘要

伽马辐照是一种用于农业中对有害微生物进行消毒的非热加工技术。该技术已被证明是控制细菌性和真菌性植物病原体的有效方法。然而,其对病毒性植物病原体的影响尚不太清楚。对伽马辐照灭活烟草花叶病毒(TMV)进行了评估。辐照后,TMV的感染力呈剂量依赖性逐渐下降,在剂量超过40千戈瑞时病毒被完全灭活。透射电子显微镜显示,增加伽马辐照会破坏病毒粒子结构并降解病毒蛋白,从而导致TMV失活。伽马辐照使TMV失活的机制可能与对病毒成分的损伤直接相关。

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1
Inactivation of tobacco mosaic virus using gamma irradiation and its potential modes of action.利用伽马射线辐照使烟草花叶病毒失活及其潜在作用模式。
Acta Virol. 2017;61(2):223-225. doi: 10.4149/av_2017_02_14.
2
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