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对于TRICARE保险儿童复发性急性中耳炎,鼓膜置管术与药物治疗的比较

Tympanostomy Tube Placement vs Medical Management for Recurrent Acute Otitis Media in TRICARE-Insured Children.

作者信息

Raol Nikhila, Sharma Meesha, Boss Emily F, Jiang Wei, Scott John W, Learn Peter, Weissman Joel S

机构信息

1 Center for Surgery and Public Health, Harvard Medical School and Harvard T. H. Chan School of Public Health, Department of Surgery, Brigham & Women's Hospital, Boston, Massachusetts, USA.

2 Department of Otolaryngology, Emory University, Atlanta, Georgia, USA.

出版信息

Otolaryngol Head Neck Surg. 2017 Nov;157(5):867-873. doi: 10.1177/0194599817707718. Epub 2017 May 23.

Abstract

Objective To compare number of infections and health care utilization in children insured by TRICARE with recurrent acute otitis media (RAOM) managed surgically with tympanostomy tube (TT) placement compared with those managed medically. Study Design Retrospective matched cohort study. Setting TRICARE claims database from 2006 to 2010. Subjects and Methods We matched TRICARE beneficiaries ≤5 years of age diagnosed with RAOM who underwent TT placement with those managed medically using 1:1 coarsened-exact matching on age, sex, race, sponsor rank, and region. We used multivariable negative binomial regression to compare number of infections and health care utilization at 1 and 2 years. Outcomes were adjusted for rate of infection before treatment for RAOM, season of either TT placement or establishment of candidacy for TT placement, and comorbidities. Results Among 6659 pairs identified at 1-year follow-up, the TT group had fewer infections (1.96 vs 2.18, P < .001) and oral antibiotic prescriptions (1.52 vs 1.67, P < .001) but more visits to primary care physicians (4.36 vs 4.06, P < .0001) and otolaryngologists (1.21 vs 0.44, P < .0001) compared with the medically managed group. At 2-year follow-up, the benefits of TT placement were no longer seen. Conclusion TT placement for RAOM is associated with fewer infections and oral antibiotic prescriptions in the first year after surgery but more doctor visits. Benefits of TT placement do not appear to extend through the second year. Future research should investigate costs associated with TT placement vs medical management, as well as real-time health care utilization with impact on patient symptoms and quality of life.

摘要

目的 比较由军事医疗保健计划(TRICARE)承保的复发性急性中耳炎(RAOM)患儿经鼓膜置管术(TT)手术治疗与药物治疗的感染次数和医疗保健利用率。研究设计 回顾性匹配队列研究。研究背景 2006年至2010年的TRICARE索赔数据库。研究对象与方法 我们将年龄≤5岁、被诊断为RAOM且接受TT置管术的TRICARE受益人,与采用年龄、性别、种族、担保人职级和地区1:1精确匹配法进行药物治疗的受益人进行匹配。我们使用多变量负二项回归来比较1年和2年时的感染次数和医疗保健利用率。对RAOM治疗前的感染率、TT置管时间或确定TT置管候选资格的季节以及合并症进行了结果校正。结果 在1年随访中确定的6659对病例中,与药物治疗组相比,TT组感染次数(1.96比2.18,P<.001)和口服抗生素处方数(1.52比1.67,P<.001)更少,但到初级保健医生处就诊次数(4.36比4.06,P<.0001)和耳鼻喉科医生处就诊次数(1.21比0.44,P<.0001)更多。在2年随访时,未再观察到TT置管术的益处。结论 RAOM患儿TT置管术在术后第一年与感染次数减少和口服抗生素处方数减少相关,但就诊次数更多。TT置管术的益处似乎不会持续到第二年。未来的研究应调查TT置管术与药物治疗相关的成本,以及对患者症状和生活质量有影响的实时医疗保健利用率。

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