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未使用硬膜外麻醉的产妇在第二产程中的体位。

Position in the second stage of labour for women without epidural anaesthesia.

作者信息

Gupta Janesh K, Sood Akanksha, Hofmeyr G Justus, Vogel Joshua P

机构信息

Academic Department of Obstetrics and Gynaecology, University of Birmingham, Birmingham Women's Hospital, Edgbaston, Birmingham, UK, B15 2TG.

Department of Obstetrics and Gynaecology, St Mary’s Hospital, CMFT, Oxford Road, Manchester, UK, M13 9WL.

出版信息

Cochrane Database Syst Rev. 2017 May 25;5(5):CD002006. doi: 10.1002/14651858.CD002006.pub4.

Abstract

BACKGROUND

For centuries, there has been controversy around whether being upright (sitting, birthing stools, chairs, squatting, kneeling) or lying down (lateral (Sim's) position, semi-recumbent, lithotomy position, Trendelenburg's position) have advantages for women giving birth to their babies. This is an update of a review previously published in 2012, 2004 and 1999.

OBJECTIVES

To determine the possible benefits and risks of the use of different birth positions during the second stage of labour without epidural anaesthesia, on maternal, fetal, neonatal and caregiver outcomes.

SEARCH METHODS

We searched Cochrane Pregnancy and Childbirth's Trials Register (30 November 2016) and reference lists of retrieved studies.

SELECTION CRITERIA

Randomised, quasi-randomised or cluster-randomised controlled trials of any upright position assumed by pregnant women during the second stage of labour compared with supine or lithotomy positions. Secondary comparisons include comparison of different upright positions and the supine position. Trials in abstract form were included.

DATA COLLECTION AND ANALYSIS

Two review authors independently assessed trials for inclusion and assessed trial quality. At least two review authors extracted the data. Data were checked for accuracy. The quality of the evidence was assessed using the GRADE approach.

MAIN RESULTS

Results should be interpreted with caution because risk of bias of the included trials was variable. We included eleven new trials for this update; there are now 32 included studies, and one trial is ongoing. Thirty trials involving 9015 women contributed to the analysis. Comparisons include any upright position, birth or squat stool, birth cushion, and birth chair versus supine positions.In all women studied (primigravid and multigravid), when compared with supine positions, the upright position was associated with a reduction in duration of second stage in the upright group (MD -6.16 minutes, 95% CI -9.74 to -2.59 minutes; 19 trials; 5811 women; P = 0.0007; random-effects; I² = 91%; very low-quality evidence); however, this result should be interpreted with caution due to large differences in size and direction of effect in individual studies. Upright positions were also associated with no clear difference in the rates of caesarean section (RR 1.22, 95% CI 0.81 to 1.81; 16 trials; 5439 women; low-quality evidence), a reduction in assisted deliveries (RR 0.75, 95% CI 0.66 to 0.86; 21 trials; 6481 women; moderate-quality evidence), a reduction in episiotomies (average RR 0.75, 95% CI 0.61 to 0.92; 17 trials; 6148 women; random-effects; I² = 88%), a possible increase in second degree perineal tears (RR 1.20, 95% CI 1.00 to 1.44; 18 trials; 6715 women; I² = 43%; low-quality evidence), no clear difference in the number of third or fourth degree perineal tears (RR 0.72, 95% CI 0.32 to 1.65; 6 trials; 1840 women; very low-quality evidence), increased estimated blood loss greater than 500 mL (RR 1.48, 95% CI 1.10 to 1.98; 15 trials; 5615 women; I² = 33%; moderate-quality evidence), fewer abnormal fetal heart rate patterns (RR 0.46, 95% CI 0.22 to 0.93; 2 trials; 617 women), no clear difference in the number of babies admitted to neonatal intensive care (RR 0.79, 95% CI 0.51 to 1.21; 4 trials; 2565 infants; low-quality evidence). On sensitivity analysis excluding trials with high risk of bias, these findings were unchanged except that there was no longer a clear difference in duration of second stage of labour (MD -4.34, 95% CI -9.00 to 0.32; 21 trials; 2499 women; I² = 85%).The main reasons for downgrading of GRADE assessment was that several studies had design limitations (inadequate randomisation and allocation concealment) with high heterogeneity and wide CIs.

AUTHORS' CONCLUSIONS: The findings of this review suggest several possible benefits for upright posture in women without epidural anaesthesia, such as a very small reduction in the duration of second stage of labour (mainly from the primigravid group), reduction in episiotomy rates and assisted deliveries. However, there is an increased risk blood loss greater than 500 mL and there may be an increased risk of second degree tears, though we cannot be certain of this. In view of the variable risk of bias of the trials reviewed, further trials using well-designed protocols are needed to ascertain the true benefits and risks of various birth positions.

摘要

背景

几个世纪以来,关于分娩时采用直立姿势(坐、使用分娩凳、椅子、蹲、跪)还是躺卧姿势(侧卧位(辛氏卧位)、半卧位、截石位、头低足高位)对产妇是否有优势一直存在争议。这是对之前于2012年、2004年和1999年发表的一篇综述的更新。

目的

确定在第二产程中未使用硬膜外麻醉时,采用不同分娩姿势对产妇、胎儿、新生儿及医护人员结局的潜在益处和风险。

检索方法

我们检索了Cochrane妊娠与分娩试验注册库(2016年11月30日)以及检索到的研究的参考文献列表。

选择标准

将孕妇在第二产程中采用的任何直立姿势与仰卧位或截石位进行比较的随机、半随机或整群随机对照试验。次要比较包括不同直立姿势与仰卧位的比较。纳入摘要形式的试验。

数据收集与分析

两位综述作者独立评估试验是否纳入并评估试验质量。至少两位综述作者提取数据。检查数据准确性。采用GRADE方法评估证据质量。

主要结果

由于纳入试验的偏倚风险各异,对结果的解释应谨慎。本次更新纳入了11项新试验;目前共有32项纳入研究,还有1项试验正在进行。30项涉及9015名女性的试验纳入了分析。比较包括任何直立姿势、分娩凳或蹲凳、分娩垫和分娩椅与仰卧位。在所有研究的女性(初产妇和经产妇)中,与仰卧位相比,直立姿势组第二产程持续时间缩短(MD -6.16分钟,95%CI -9.74至-2.59分钟;19项试验;5811名女性;P = 0.0007;随机效应;I² = 91%;极低质量证据);然而,由于各研究在效应大小和方向上存在较大差异,该结果的解释应谨慎。直立姿势与剖宫产率无明显差异(RR 1.22,95%CI 0.81至1.81;16项试验;5439名女性;低质量证据)、助产分娩减少(RR 0.75,95%CI 0.66至0.86;21项试验;6481名女性;中等质量证据)、会阴切开术减少(平均RR 0.75,95%CI 0.61至0.92;17项试验;6148名女性;随机效应;I² = 88%)、二度会阴撕裂可能增加(RR 1.20,95%CI 1.00至1.44;18项试验;6715名女性;I² = 43%;低质量证据)、三度或四度会阴撕裂数量无明显差异(RR 0.72,95%CI 0.32至1.65;6项试验;1840名女性;极低质量证据)、估计失血量超过500 mL增加(RR 1.48,95%CI 1.10至1.98;15项试验;5615名女性;I² = 33%;中等质量证据)、异常胎儿心率模式减少(RR 0.46,95%CI 0.22至0.93;2项试验;617名女性)、入住新生儿重症监护病房的婴儿数量无明显差异(RR 0.79,95%CI 0.51至1.21;4项试验;2565名婴儿;低质量证据)。在排除高偏倚风险试验的敏感性分析中,这些结果未变,只是第二产程持续时间不再有明显差异(MD -4.34,95%CI -9.00至0.32;21项试验;2499名女性;I² = 85%)。GRADE评估降级的主要原因是多项研究存在设计局限性(随机化和分配隐藏不足),异质性高且置信区间宽。

作者结论

本综述结果表明,对于未使用硬膜外麻醉的女性,直立姿势可能有若干益处,如第二产程持续时间略有缩短(主要来自初产妇组)、会阴切开术率和助产分娩减少。然而,失血量超过500 mL的风险增加,二度撕裂风险可能增加,尽管我们不能确定。鉴于所综述试验的偏倚风险各异,需要进一步采用设计良好的方案进行试验,以确定各种分娩姿势的真正益处和风险。

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