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术中使用氯丙嗪预防主动脉冠状动脉旁路移植术中桡动脉痉挛

Intraoperative chlorpromazine treatment for prevention of radial artery spasm in aortocoronary bypass grafting.

作者信息

Shipulin Vladimir, Kozlov Boris, Nasrashvili Georgiy, Zatolokin Vasiliy, Kuznetsov Mikhael, Panfilov Dmitry, Afanas'ev Sergey

机构信息

Department of Cardiovascular Surgery, Cardiology Research Institute, Tomsk NRMC, Tomsk, Russia.

出版信息

Interact Cardiovasc Thorac Surg. 2017 Sep 1;25(3):493-495. doi: 10.1093/icvts/ivx143.

Abstract

A detailed description of intraoperative prevention of radial artery graft spasm using a solution of the calmodulin inhibitor chlorpromazine is presented. This method is used in direct myocardial revascularization and can reliably prevent perioperative spasm of radial artery grafts, as confirmed by intraoperative flow measurement, bypass angiography in the postoperative period, and in vitro experimental data.

摘要

本文详细描述了使用钙调蛋白抑制剂氯丙嗪溶液在术中预防桡动脉移植血管痉挛的方法。该方法用于直接心肌血运重建,并且通过术中血流测量、术后旁路血管造影以及体外实验数据证实,能够可靠地预防桡动脉移植血管的围手术期痉挛。

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