Kissoon Narayan R, Cutrer Fred Michael
Division of Headache, Department of Neurology, Mayo Clinic, Rochester, MN, USA .
Headache. 2017 Jul;57(7):1179-1194. doi: 10.1111/head.13101. Epub 2017 May 19.
Migraine can present with a wide range of neurological symptoms.
Based on currently available data, the symptoms of typical migraine aura are most likely related to cortical spreading depression (CSD), and evidence supports that CSD can lead to trigeminovascular activation resulting in the headache phase of migraine.
An alternative diagnosis to migraine aura should be considered if migrainous headaches present with transient neurological symptoms that have features inconsistent with aura.
偏头痛可伴有多种神经症状。
根据现有数据，典型偏头痛先兆症状最有可能与皮层扩散性抑制（CSD）有关，且有证据支持CSD可导致三叉神经血管激活，从而引发偏头痛的头痛期。
如果偏头痛性头痛伴有与先兆特征不符的短暂神经症状，则应考虑偏头痛先兆的替代诊断。
