选择性激光小梁成形术后青光眼患者的生活质量
Quality of life in glaucoma patients after selective laser trabeculoplasty.
作者信息
De Keyser Myrjam, De Belder Maya, De Groot Veva
机构信息
Department of Medicine, University of Antwerp, Univer-siteitsplein 1, Antwerp B-2610, Belgium.
Department of Experimental Psychology, Ghent University, Henri Dunantlaan 2, Ghent B-9000, Belgium.
出版信息
Int J Ophthalmol. 2017 May 18;10(5):742-748. doi: 10.18240/ijo.2017.05.14. eCollection 2017.
AIM
To compare quality of life and treatment satisfaction between patients who had selective laser trabeculoplasty (SLT) and those on medication.
METHODS
A prospective clinical trial on 143 glaucoma patients that received SLT and a control group that continued using anti glaucoma medication was conducted. Tear break-up time (BUT), punctuate keratitis, need for help, use of artificial tears and the treatment satisfaction survey of intraocular pressure (IOP) were measured at baseline, 6 and 12mo.
RESULTS
SLT was able to reduce the mean number of medications needed from 1.56±0.81 to 0.42±0.66 at six months and to 0.33±0.69 at one year. Punctuate keratitis was observed significantly less often (12.24%) after SLT than before (35.94%; =0.03). Use of artificial tears and BUT did not change significantly after SLT (>0.05). At baseline, patients in the SLT group were significantly less convinced of medication effectiveness (=0.006) and complained more about side effects (=0.003). After SLT, these patients had significantly more confidence in their therapy (<0.001), showed less side effects (=0.006), complained less about changes in appearance of the eyes (=0.003) and were less inconvenienced by the use of eye drops (<0.001).
CONCLUSION
SLT is able to improve treatment-related quality of life in glaucoma patients.
目的
比较接受选择性激光小梁成形术（SLT）的患者与药物治疗患者的生活质量和治疗满意度。
方法
对143例接受SLT的青光眼患者和继续使用抗青光眼药物的对照组进行了一项前瞻性临床试验。在基线、6个月和12个月时测量泪膜破裂时间（BUT）、点状角膜炎、求助需求、人工泪液使用情况以及眼压治疗满意度调查。
结果
SLT能够将所需药物的平均数量从6个月时的1.56±0.81减少到0.42±0.66，1年时减少到0.33±0.69。SLT后观察到点状角膜炎的发生率显著低于术前（12.24%对35.94%；P=0.03）。SLT后人工泪液的使用和BUT没有显著变化（P>0.05）。在基线时，SLT组的患者对药物疗效的信心明显较低（P=0.006），对副作用的抱怨更多（P=0.003）。SLT后，这些患者对治疗的信心明显增强（P<0.001），副作用更少（P=0.006），对眼部外观变化的抱怨更少（P=0.003），使用眼药水带来的不便也更少（P<0.001）。
结论
SLT能够改善青光眼患者与治疗相关的生活质量。
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