持续肾脏替代疗法在脓毒症急性肾损伤中的作用

The Roles of Continuous Renal Replacement Therapy in Septic Acute Kidney Injury.

作者信息

Ueno Takuya

机构信息

Transplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Division of Critical Care and Emergency Medicine, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan.

出版信息

Artif Organs. 2017 Jul;41(7):667-672. doi: 10.1111/aor.12941. Epub 2017 May 26.

DOI:10.1111/aor.12941

PMID:28548696

Abstract

Despite hundreds of clinical and basic studies that have led to a better mechanistic understanding of sepsis, the number of cases with sepsis in the United States is still rising. Sepsis is a common cause of acute kidney injury (AKI) and may explain long-term complications and mortality. In the current article, a new therapeutic concept using continuous renal replacement therapy to prevent and manage long-term sequelae in septic AKI is described.

摘要

尽管已有数百项临床和基础研究，使人们对脓毒症的发病机制有了更深入的了解，但美国脓毒症病例的数量仍在上升。脓毒症是急性肾损伤（AKI）的常见病因，可能是长期并发症和死亡的原因。在当前这篇文章中，描述了一种使用连续性肾脏替代疗法预防和管理脓毒症相关性急性肾损伤长期后遗症的新治疗理念。