Coupal Tyler Michael, Chang David Ross, Pennycooke Kevin, Ouellette Hugue Alcide, Munk Peter Loren
Department of Radiology, Vancouver General Hospital, Vancouver, British Columbia, Canada.
J Radiol Case Rep. 2017 Apr 30;11(4):30-37. doi: 10.3941/jrcr.v11i4.3092. eCollection 2017 Apr.
Throughout recent years, Gabapentin has become increasingly used for the treatment of neuropathic pain. We report on a case of a 31 year old female who presented to the emergency department with unilateral leg pain, weakness, and swelling after increasingly titrating her Gabapentin dosage over three weeks. Magnetic resonance imaging confirmed the presence of myositis confined to the left thigh and the patient's symptoms and laboratory abnormalities resolved following Gabapentin cessation. While Gabapentin-induced myositis and rhabdomyolysis is a rare entity, it should be a diagnostic consideration for radiologists, particularly in the absence of infection or trauma.
近年来,加巴喷丁越来越多地用于治疗神经性疼痛。我们报告了一例31岁女性病例,该患者在三周内逐渐增加加巴喷丁剂量后,因单侧腿痛、无力和肿胀而就诊于急诊科。磁共振成像证实存在局限于左大腿的肌炎,停用加巴喷丁后患者的症状和实验室异常情况得到缓解。虽然加巴喷丁诱发的肌炎和横纹肌溶解是一种罕见的情况,但放射科医生应将其作为一种诊断考虑因素,尤其是在没有感染或创伤的情况下。