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马里兰州癫痫患者驾驶员管理:美国共识指南应用结果。

Regulating drivers with epilepsy in Maryland: Results of the application of a United States consensus guideline.

机构信息

Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, U.S.A.

Tulane University School of Medicine, New Orleans, Louisiana, U.S.A.

出版信息

Epilepsia. 2017 Aug;58(8):1389-1397. doi: 10.1111/epi.13804. Epub 2017 Jun 1.

Abstract

OBJECTIVE

Driving regulations for people with seizures vary widely throughout the United States and the world. Maryland updated their guidelines in 2003 to reflect those of a U.S. consensus guideline requiring a minimum 3-month seizure-free period as well as an individual risk assessment by a Medical Advisory Board (MAB). This retrospective study provides the first analysis of outcomes after the implementation of the consensus guidelines and an assessment of their predictive validity through longitudinal outcome data.

METHODS

MAB reviews and licensing records for Maryland driver applicants with seizures between 2004 and 2005 were reviewed, during which 254 first-time applicants were processed. The initial licensing decisions were assessed and the subsequent seizure recurrence and crash rates over the following 7 years were evaluated.

RESULTS

The MAB approved driving for 74.8% of initial applicants; most had been seizure-free for over 6 months. Approved drivers had a longer median seizure-free period (563 days) compared to those who were denied (104.5 days, p < 0.01), and 22.7% of approved drivers had seizures recur during monitoring over the next year, although none resulted in crashes or deaths. Of applicants initially denied (n = 50), 89.3% were eventually licensed. Treating physicians recommended driving for 84.4% of applicants rejected by the MAB.

SIGNIFICANCE

Maryland's individualized system for assessing driving applicants with seizures resulted in a dynamic process of approvals and denials based on favorable and unfavorable risk factors and lengths of seizure freedom. Seizure recurrences were comparable to internationally accepted rates. Over the course of monitoring, most applicants were eventually licensed. Treating physicians recommended that nearly all their patient applicants be permitted to drive, which raises safety concerns for the 10 states that rely solely on physician recommendations. Further assessment is needed of the risk factors deemed favorable and unfavorable by the U.S. consensus guidelines.

摘要

目的

美国和世界各地的癫痫患者驾驶规定差异很大。马里兰州在 2003 年更新了其指南,以反映美国共识指南的规定,要求至少 3 个月无癫痫发作,以及医疗咨询委员会(MAB)的个体风险评估。这项回顾性研究首次分析了实施共识指南后的结果,并通过纵向结果数据评估了其预测有效性。

方法

审查了 2004 年至 2005 年间马里兰州癫痫患者驾驶员申请人的 MAB 审查和许可记录,在此期间处理了 254 名首次申请人。评估了初始许可决定,并评估了随后的 7 年内癫痫复发和撞车率。

结果

MAB 批准了 74.8%的初始申请人驾驶;大多数人已经无癫痫发作超过 6 个月。批准的驾驶员无癫痫发作的中位时间(563 天)明显长于被拒绝的驾驶员(104.5 天,p<0.01),在接下来的一年监测期间,22.7%的批准驾驶员癫痫复发,尽管没有导致撞车或死亡。最初被拒绝的申请人(n=50)中,89.3%最终获得许可。MAB 拒绝的申请人中,84.4%的主治医生建议驾驶。

意义

马里兰州评估癫痫患者驾驶申请人的个体化系统导致了根据有利和不利风险因素以及无癫痫发作时间的批准和拒绝的动态过程。癫痫复发与国际公认的比率相当。在监测过程中,大多数申请人最终获得许可。主治医生建议允许他们的几乎所有患者申请人驾驶,这对仅依赖医生建议的 10 个州的安全提出了担忧。需要进一步评估美国共识指南认为有利和不利的风险因素。

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