肝细胞癌立体定向体部放射治疗的进展
Advances in Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma.
作者信息
Murray Louise J, Dawson Laura A
机构信息
Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada; Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada; Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
出版信息
Semin Radiat Oncol. 2017 Jul;27(3):247-255. doi: 10.1016/j.semradonc.2017.02.002. Epub 2017 Feb 20.
Stereotactic Body Radiation Therapy (SBRT) is an emerging effective treatment for hepatocellular carcinoma (HCC) associated with acceptable rates of toxicity in appropriately selected patients. Despite often being reserved for patients unsuitable for other local treatments, prospective and retrospective studies have demonstrated excellent long-term control. SBRT may be used as a stand-alone treatment, or as an adjunct to other HCC therapies. Based on available data, SBRT appears to complement existing local liver therapies. Randomized and nonrandomized comparative studies are required to better determine the optimal role of SBRT in HCC treatment.
立体定向体部放射治疗（SBRT）是一种新兴的有效治疗肝细胞癌（HCC）的方法，在适当选择的患者中，其毒性发生率可接受。尽管SBRT通常用于不适宜接受其他局部治疗的患者，但前瞻性和回顾性研究均显示其具有出色的长期控制效果。SBRT可作为单一治疗方法使用，也可作为其他肝癌治疗的辅助手段。根据现有数据，SBRT似乎可以补充现有的肝脏局部治疗方法。需要进行随机和非随机比较研究，以更好地确定SBRT在肝癌治疗中的最佳作用。
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