Aghili Rokhsareh, Ridderstråle Martin, Kia Maryam, Ebrahim Valojerdi Ameneh, Malek Mojtaba, Farshchi Amir, Khamseh Mohammad Ebrahim
Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran.
Department of Clinical Sciences, Clinical Obesity, Lund University, Skåne University Hospital Malmö, S-205 02 Malmö, Sweden.
Prim Care Diabetes. 2017 Oct;11(5):467-473. doi: 10.1016/j.pcd.2017.05.001. Epub 2017 May 31.
Attitudes toward diabetes care are different between genders and age-groups. Furthermore, diabetes related challenges may cause psychosocial problems. Therefore, we were to compare the psychosocial status and glycemic control in women and men with type 2 diabetes (T2D) in different age-groups.
441 adults with T2D were recruited. Demographic, self-care behavior, resources and affective variables as well as the health related quality of life (HRQoL) were measured. The median age of 55 was used as the cut-off for the age comparison. Structured equation modeling (SEM) investigated the relationship between age, gender, psychosocial factors and glycemic control.
Finally, 203 women and 177 men completed the study (86.1%). There was no significant difference in mean duration of T2D, or glycemic control between genders or age-groups. Women, especially those below the median age of 55, had significantly higher level of diabetes-related distress (2.16±0.94 vs. 1.92±0.81), depression (9.67±5.37 vs. 7.54±5.06), and anxiety (19.81±12.04 vs. 12.81±9.04, P<0.05 for all comparisons), while people above the age of 55 reported better self-management and patient-physician relationship. HRQoL was lower in women compared to men (0.77±0.23 vs. 0.81±0.18, P=0.02). The final SEM suggested that the effect (standardized β coefficient) of gender and age on affective variables was 0.25 and -0.19 (P<0.05), respectively, though psychosocial factors did not directly influence HbA1c.
This study shows that psychosocial factors are associated with age and gender in patients with T2D; with younger women demonstrating higher level of depressive symptoms, anxiety, and diabetes-related distress independent of status of glycemic control.
不同性别和年龄组对糖尿病护理的态度存在差异。此外,与糖尿病相关的挑战可能会导致心理社会问题。因此,我们旨在比较不同年龄组的2型糖尿病(T2D)女性和男性的心理社会状况及血糖控制情况。
招募了441名成年T2D患者。测量了人口统计学、自我护理行为、资源和情感变量以及健康相关生活质量(HRQoL)。以55岁的中位数年龄作为年龄比较的分界点。采用结构方程模型(SEM)研究年龄、性别、心理社会因素与血糖控制之间的关系。
最终,203名女性和177名男性完成了研究(86.1%)。T2D的平均病程或血糖控制在性别或年龄组之间没有显著差异。女性,尤其是年龄低于55岁中位数的女性,糖尿病相关困扰水平(2.16±0.94对1.92±0.81)、抑郁水平(9.67±5.37对7.54±5.06)和焦虑水平(19.81±12.04对12.81±9.04,所有比较P<0.05)显著更高,而55岁以上的人自我管理和医患关系更好。女性的HRQoL低于男性(0.77±0.23对0.81±0.18,P=0.02)。最终的SEM表明,性别和年龄对情感变量的影响(标准化β系数)分别为0.25和-0.19(P<0.05),尽管心理社会因素并未直接影响糖化血红蛋白(HbA1c)。
本研究表明,心理社会因素与T2D患者的年龄和性别相关;年轻女性表现出更高水平的抑郁症状、焦虑和糖尿病相关困扰,且独立于血糖控制状况。