Celik Mehmet, Guldiken Sibel, Ayturk Semra, Bulbul Buket Yilmaz, Tastekin Ebru, Can Nuray, Sezer Atakan, Ustun Funda, Kucukarda Ahmet
Department of Endocrinology and Metabolism, Medical Faculty, Trakya University, Edirne, Turkey.
Department of Pathology, Medical Faculty, Trakya University, Edirne, Turkey.
Int J Appl Basic Med Res. 2017 Apr-Jun;7(2):117-120. doi: 10.4103/2229-516X.205806.
This study aimed to evaluate concurrently detected thyroid pathologies in the patients who underwent surgery for primary hyperparathyroidism (PHPT).
In this study, we retrospectively analyzed the files of the patients who underwent surgery for PHPT between 2012 and 2015. Pre- and post-operative laboratory examination results and preoperative radiological and nuclear medicine findings of the patients were retrospectively recorded.
A total number of 41 patients with PHPT were divided into two groups as the Group 1 with PHPT and benign thyroid pathology (21 patients) and the Group 2 with PHPT and malignant thyroid pathology (20 patients). In Group 1, 18 and 3 of 21 patients were females and males, respectively. Group 2 included 15 male and 5 female patients. The mean age of the patients was found to be 55.6 and 53.9 years in Group 1 and Group 2, respectively. Both groups were matched for age and gender. In terms of thyroid pathology, 20 of 41 patients (48.7%) who underwent total thyroidectomy for PHPT were found to have thyroid papillary carcinoma while benign pathologic conditions were detected in 21 (51.3%) individuals.
Cooccurrence of thyroid diseases and PHPT is common. Therefore, all the patients should preoperatively be evaluated for the presence of thyroid pathology to determine the technique of parathyroid surgery.
本研究旨在评估原发性甲状旁腺功能亢进症(PHPT)手术患者中同时检测到的甲状腺病变情况。
在本研究中,我们回顾性分析了2012年至2015年间接受PHPT手术患者的病历。回顾性记录患者术前和术后的实验室检查结果以及术前的放射学和核医学检查结果。
41例PHPT患者共分为两组,第1组为患有PHPT和良性甲状腺病变的患者(21例),第2组为患有PHPT和恶性甲状腺病变的患者(20例)。在第1组中,21例患者中有18例女性和3例男性。第2组包括15例男性和5例女性患者。第1组和第2组患者的平均年龄分别为55.6岁和53.9岁。两组在年龄和性别方面相匹配。在甲状腺病变方面,41例因PHPT接受全甲状腺切除术的患者中有20例(48.7%)被发现患有甲状腺乳头状癌,而21例(51.3%)个体检测到良性病理状况。
甲状腺疾病与PHPT同时存在很常见。因此,所有患者术前均应评估是否存在甲状腺病变,以确定甲状旁腺手术技术。