Pokrovskiĭ A V, Ignat'ev I M, Gradusov E G, Bredikhin R A
Institute of Surgery named after A.V. Vishnevsky under the RF Ministry of Public Health, Moscow, Russia; Russian Medical Academy of Continuous Professional Education, under the RF Ministry of Public Health, Moscow, Russia.
Interregional Clinical Diagnostic Centre, Kazan, Russia; Kazan State Medical University of the RF Ministry of Public Health, Kazan, Russia.
Angiol Sosud Khir. 2017;23(2):177-184.
The study was aimed at assessing efficacy of open thrombectomy in acute iliofemoral venous thrombosis.
From January 2012 to December 2016, a total of 37 patients underwent transfemoral thrombectomy for acute iliofemoral venous thrombosis. The Control Group consisted of 24 patients receiving standard anticoagulant therapy. Six patients were subjected to a hybrid operation consisting in thrombectomy supplemented with stenting of the residual compression stenosis of the left common iliac vein (CIV). The outcomes of the operations were controlled by means of duplex scanning. Clinical efficacy of the operations was evaluated with the help of the Venous Clinical Severity Score (VCSS) and CEAP classification.
Patency of the iliofemoral segment at 6 months of follow up after thrombectomy was observed in 92% of patients. At the same time, in patients receiving anticoagulant therapy recanalization of the iliofemoral segment was observed in only 21% (5/24; χ2=31, p<0.01) of cases. Recanalization of the femoropopliteal segment 6 months after thrombectomy was noted to occur in 70% (23/33) of patients. The median of the composite index by the VCSS after 6 months decreased from 7 to 2 (p=0.002). The cumulative patency of the iliofemoral segment 36 months after surgery amounted to 86%. Clinical assessment of the remote results of thrombectomy according to the CEAP classification demonstrated that 90% (19/21) of patients were either free from or had weakly pronounced symptoms of post-thrombotic syndrome.
Performing thrombectomy for iliofemoral thrombosis by selective indications using modern methods of restoring patency of deep veins significantly increases efficacy of treating patients presenting with this severe pathology and prevents the development of pronounced manifestations of post-thrombotic syndrome.
本研究旨在评估开放性血栓切除术治疗急性髂股静脉血栓形成的疗效。
2012年1月至2016年12月,共有37例患者接受了经股动脉血栓切除术治疗急性髂股静脉血栓形成。对照组由24例接受标准抗凝治疗的患者组成。6例患者接受了混合手术,包括血栓切除术并辅以左髂总静脉(CIV)残余压迫性狭窄的支架置入术。通过双功扫描控制手术结果。借助静脉临床严重程度评分(VCSS)和CEAP分类评估手术的临床疗效。
血栓切除术后6个月,92%的患者髂股段通畅。与此同时,接受抗凝治疗的患者中,髂股段再通的仅占21%(5/24;χ2=31,p<0.01)。血栓切除术后6个月,70%(23/33)的患者股腘段再通。6个月后VCSS综合指数的中位数从7降至2(p=0.002)。术后36个月髂股段的累积通畅率为86%。根据CEAP分类对血栓切除术远期结果进行的临床评估表明,90%(19/21)的患者无血栓形成后综合征症状或症状轻微。
采用现代恢复深静脉通畅的方法,根据选择性指征对髂股静脉血栓形成进行血栓切除术,可显著提高治疗这种严重疾病患者的疗效,并预防血栓形成后综合征的明显表现。