卒中后癫痫的进展。
The Progress of Epilepsy after Stroke.
机构信息
Department of Thoracic Surgery, The Second Hospital of Jilin University; Jilin Provincial Key Laboratory on Molecular and Chemical Genetic, Changchun, Jilin, China.
Center of Chinese Medicine and Bio-Engineering Research and Development, Changchun University of Chinese Medicine, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, Jilin, China.
出版信息
Curr Neuropharmacol. 2018;16(1):71-78. doi: 10.2174/1570159X15666170613083253.
BACKGROUND
Epilepsy is the second most common disease caused by multiple factors and characterized by an excessive discharge of certain neurons in the nervous system. Cerebrovascular disease, including stroke, is viewed as the most common cause of epilepsy in the elderly population, accounting for 30%-50% of the newly diagnosed cases of epilepsy cases in this age group.
METHODS
Data were collected from Web of Science, Medline, Pubmed, Scopus, through searching of these keywords: "Stroke" and "epilepsy".
RESULTS
Depending on the underlying cerebrovascular disease, 3%-30% of patients after stroke may develop post-stroke epilepsy (PSE), which has a negative effect on stroke prognosis and the quality of life.
CONCLUSION
In this review, we summarized new aspects emerging from research into PSE, including definition, epidemiology, risk factors, mechanism, accessory examination and treatment strategies for post-stroke epilepsy, which will enrich our knowledge of this disorder.
背景
癫痫是由多种因素引起的第二大常见疾病，其特征是神经系统中某些神经元过度放电。脑血管病，包括中风，被认为是老年人癫痫最常见的病因，占该年龄段新诊断癫痫病例的 30%-50%。
方法
我们从 Web of Science、Medline、Pubmed、Scopus 等数据库中收集数据，通过搜索“Stroke”和“epilepsy”这两个关键词来获取相关数据。
结果
根据潜在的脑血管疾病，3%-30%的中风患者可能会发生中风后癫痫（PSE），这对中风预后和生活质量有负面影响。
结论
在本综述中，我们总结了中风后癫痫研究中的新方面，包括定义、流行病学、危险因素、发病机制、辅助检查和治疗策略，这将丰富我们对这种疾病的认识。
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