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与年轻胃癌患者相比,八旬及以上老年患者微创与开放手术的手术结果比较:一项回顾性队列研究。

Comparison of the surgical outcomes of minimally invasive and open surgery for octogenarian and older compared to younger gastric cancer patients: a retrospective cohort study.

作者信息

Liu Chien-An, Huang Kuo-Hung, Chen Ming-Huang, Lo Su-Shun, Li Anna Fen-Yau, Wu Chew-Wun, Shyr Yi-Ming, Fang Wen-Liang

机构信息

Department of Radiology, Taipei Veterans General Hospital, Taipei City, Taiwan.

School of Medicine, National Yang-Ming University, Taipei City, Taiwan.

出版信息

BMC Surg. 2017 Jun 12;17(1):68. doi: 10.1186/s12893-017-0265-3.

Abstract

BACKGROUND

As life expectancy continues to increase around the world, the use of minimally invasive surgery (MIS) could be beneficial for octogenarian and older gastric cancer patients.

METHODS

A total of 359 gastric cancer patients who underwent curative surgery between March 2011 and March 2015 were enrolled; 80 of these patients (22.2%) were octogenarians and older. Surgical approaches included MIS (50 laparoscopic and 65 robotic) and open surgery (n = 244). Surgical outcomes of MIS and open surgery in octogenarian and older patients were compared with younger patients.

RESULTS

Among octogenarian and older patients, relative to open surgery (n = 53), MIS (n = 27) was associated with less operative blood loss, a shorter postoperative hospital stay and similar rates of surgical complications and mortality. For MIS (n = 115), octogenarian and older patients exhibited similar postoperative outcomes to those of younger patients. For open surgery (n = 244), relative to younger patients, octogenarian and older patients experienced longer postoperative hospital stays, a higher rate of wound infection and a higher incidence of pneumonia.

CONCLUSIONS

MIS for gastric cancer is beneficial and can be performed safely in octogenarian and older patients.

摘要

背景

随着全球预期寿命的持续增长,微创手术(MIS)的应用可能对80岁及以上的老年胃癌患者有益。

方法

纳入2011年3月至2015年3月期间接受根治性手术的359例胃癌患者;其中80例患者(22.2%)为80岁及以上老年人。手术方式包括微创手术(50例腹腔镜手术和65例机器人手术)和开放手术(n = 244)。将80岁及以上患者中微创手术和开放手术的手术结果与年轻患者进行比较。

结果

在80岁及以上患者中,相对于开放手术(n = 53),微创手术(n = 27)与术中失血量更少、术后住院时间更短以及手术并发症和死亡率相似相关。对于微创手术(n = 115),80岁及以上患者的术后结果与年轻患者相似。对于开放手术(n = 244),相对于年轻患者,80岁及以上患者术后住院时间更长、伤口感染率更高且肺炎发生率更高。

结论

胃癌的微创手术是有益的,并且可以在80岁及以上患者中安全进行。

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本文引用的文献

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