Li Liuyang, Cheng George P M, Ng Alex L K, Chan Tommy C Y, Jhanji Vishal, Wang Yan
*Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, China; †Hong Kong Laser Eye Center, Hong Kong, China; ‡Department of Ophthalmology, The University of Hong Kong, Hong Kong, China; §Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China; ¶UPMC Eye Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; and ‖Tianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin Eye Institute, Tianjin, China.
Cornea. 2017 Aug;36(8):967-972. doi: 10.1097/ICO.0000000000001264.
To study the effect of myopia on the pattern change in higher-order aberrations after small incision lenticule extraction.
Sixty eyes of 60 patients were included: low myopia (≤-3.00 D), moderate myopia (-3.00 D to -6.00 D), and high myopia (≥-6.00 D). Total higher-order aberrations (tHOA), vertical coma ((Equation is included in full-text article.)), horizontal coma ((Equation is included in full-text article.)), and spherical aberration ((Equation is included in full-text article.)) were measured preoperatively and at postoperative 3 months.
At the end of 3 months, tHOA changed significantly compared with the preoperative values (P < 0.05), except for (Equation is included in full-text article.)and (Equation is included in full-text article.)in the low myopia group. The change in (Equation is included in full-text article.), (Equation is included in full-text article.), and (Equation is included in full-text article.)in the moderate group (-0.299, -0.175, and 0.108 μm) was 2.020, 4.861, and 4.696 times higher than the low group (-0.148, -0.036, 0.023 μm) (P = 0.002, 0.001, 0.001), respectively. The value in the high group (-0.331, -0.192, 0.154 μm) was 1.107, 1.097 (P = 0.478, 0.665), and 1.426 times (P = 0.047) higher than the moderate group. The degree of myopia was positively correlated with Δ(Equation is included in full-text article.)(r = 0.447; P < 0.001) and Δ(Equation is included in full-text article.)(r = 0.496; P < 0.001), and negatively correlated with ΔtHOA (r = -0.363, P = 0.004) and Δ(Equation is included in full-text article.)(r = -0.599; P < 0.001).
The study showed a different pattern of change in ocular aberrations after small incision lenticule extraction in patients with varying degrees of myopia. In patients with low myopia, there was no increase in (Equation is included in full-text article.)or (Equation is included in full-text article.). In high myopia, however, (Equation is included in full-text article.)increased with the degree of myopia, whereas the rising rate of coma was slowing.
研究近视对小切口透镜切除术高阶像差模式变化的影响。
纳入60例患者的60只眼,分为低度近视(≤-3.00 D)、中度近视(-3.00 D至-6.00 D)和高度近视(≥-6.00 D)。术前及术后3个月测量总高阶像差(tHOA)、垂直彗差((公式包含在全文中))、水平彗差((公式包含在全文中))和球差((公式包含在全文中))。
3个月末,与术前值相比,tHOA有显著变化(P<0.05),低度近视组的(公式包含在全文中)和(公式包含在全文中)除外。中度组(-0.299、-0.175和0.108μm)的(公式包含在全文中)、(公式包含在全文中)和(公式包含在全文中)变化分别比低度组(-0.148、-0.036、0.023μm)高2.020、4.861和4.696倍(P=0.002、0.001、0.001)。高度组(-0.331、-0.192、0.154μm)的值分别比中度组高1.107、1.097(P=0.478、0.665)和1.426倍(P=0.047)。近视程度与Δ(公式包含在全文中)(r=0.447;P<0.001)和Δ(公式包含在全文中)(r=0.496;P<0.001)呈正相关,与ΔtHOA(r=-0.363,P=0.004)和Δ(公式包含在全文中)(r=-0.599;P<0.001)呈负相关。
该研究显示不同程度近视患者小切口透镜切除术后眼像差变化模式不同。低度近视患者的(公式包含在全文中)或(公式包含在全文中)无增加。然而,在高度近视患者中,(公式包含在全文中)随近视程度增加,而彗差上升速率减缓。