Division of Gastroenterology, Hepatology and Nutrition, British Columbia Children's Hospital, Vancouver, BC, Canada.
Division of Gastroenterology, Hepatology and Nutrition, British Columbia Children's Hospital, Vancouver, BC, Canada.
J Infect. 2017 Jun;74 Suppl 1:S120-S127. doi: 10.1016/S0163-4453(17)30202-5.
Fecal microbiota transplantation (FMT) is a relatively simple, promising treatment for recurrent Clostridium difficile infection. While there are a wide variety of approaches including mode of delivery, the results are nonetheless encouraging, even amongst younger children. Experience with FMT in the pediatric population is increasing, showing similar success compared to adults. This article will provide an overview of C. difficile infection along with review of the rationale, methods and complications of FMT including the current experience of FMT in children.
粪便微生物移植(FMT)是一种相对简单、有前途的复发性艰难梭菌感染治疗方法。虽然有多种方法,包括输送方式,但结果仍然令人鼓舞,即使是在年幼的儿童中也是如此。在儿科人群中使用 FMT 的经验正在增加,其成功率与成人相似。本文将概述艰难梭菌感染,并回顾 FMT 的原理、方法和并发症,包括目前在儿童中使用 FMT 的经验。