地诺孕素治疗经期气胸：病例报告及激素治疗方案综述
Dienogest Therapy as a Treatment for Catamenial Pneumothorax: Case Report and Review of Hormonal Options.
作者信息
Lalani Shifana, Black Amanda, Hodge Meryl C, Tulandi Togas, Chen Innie
机构信息
Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, ON.
Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, ON; The Ottawa Hospital Research Institute, Ottawa, ON.
出版信息
J Obstet Gynaecol Can. 2017 Sep;39(9):764-768. doi: 10.1016/j.jogc.2017.01.014. Epub 2017 Jun 21.
BACKGROUND
Catamenial pneumothorax is a rare but serious condition for women of reproductive age. We describe a trial of dienogest as hormonal therapy for catamenial pneumothorax and review the literature on hormonal suppressive therapy for this condition.
CASE
A 39-year-old female, gravida 0 para 0, presented with recurrent pneumothoraces coinciding with her menses. After surgical therapy, she was started on leuprolide acetate injections for 6 months to reduce recurrence. To reduce long-term side effects of leuprolide acetate, the patient was started on dienogest 4 mg orally once daily instead of leuprolide acetate for hormonal suppression and experienced resolution of recurrent pneumothoraces.
CONCLUSION
For women with recurrent catamenial pneumothorax, dienogest may be an effective hormonal treatment option and alternative to long-term GnRH agonist therapy for long-term suppression.
背景
月经性气胸是育龄期女性罕见但严重的病症。我们描述了一项使用地诺孕素作为月经性气胸激素治疗的试验，并回顾了关于这种病症激素抑制治疗的文献。
病例
一名39岁未孕未产女性，出现与月经同时发生的复发性气胸。手术治疗后，她开始接受醋酸亮丙瑞林注射6个月以减少复发。为减少醋酸亮丙瑞林的长期副作用，患者改为口服地诺孕素4毫克，每日一次，用于激素抑制，复发性气胸得到缓解。
结论
对于复发性月经性气胸的女性，地诺孕素可能是一种有效的激素治疗选择，可替代长期使用促性腺激素释放激素激动剂进行长期抑制治疗。
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