Palmer S R, Caul E O, Donald D E, Kwantes W, Tillett H
Lancet. 1985 Nov 16;2(8464):1108-11. doi: 10.1016/s0140-6736(85)90694-4.
7 of 101 staff within one department of a large office complex had shingles, as diagnosed by a general practitioner, within a three-month period. This incidence was significantly greater than that in the remaining workforce. Varicella-zoster-specific IgM antibody was detected in all 4 cases from whom early convalescent serum samples were obtained but in none of 22 controls. Within the index department there was evidence of clustering in time and by work area. A case/control study showed that a recent preceeding illness might have been a risk factor for shingles in the outbreak cases, but not for sporadic cases in other departments of the same office complex. This outbreak suggests that shingles can be provoked by reexposure to varicella-zoster virus.
在一个大型办公区内的一个部门的101名员工中,有7人在三个月内被全科医生诊断出患有带状疱疹。这一发病率明显高于其余员工。在所有4例获得早期恢复期血清样本的病例中均检测到水痘-带状疱疹特异性IgM抗体,但在22例对照中均未检测到。在该索引部门内,有时间和工作区域聚集的证据。一项病例对照研究表明,近期的前驱疾病可能是此次疫情中带状疱疹病例的一个危险因素,但对于同一办公区内其他部门的散发病例则不是。此次疫情表明,再次接触水痘-带状疱疹病毒可能引发带状疱疹。